Evidence map›Paper›PMID 31141406›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Glycocalyx regulation of vascular endothelial growth factor receptor 2 activity.

Michelle E LeBlanc, Kahira L Saez-Torres, Issahy Cano, Zhengping Hu, Magali Saint-Geniez, Yin-Shan Ng, Patricia A D'Amore

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  10. Review
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  12. VEGFR1 signaling in retinal angiogenesis and microinflammation.Progress in retinal and eye research · 2021
    Review
  13. Article
  14. Observational
  15. Article
  16. Review
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  18. Research progress on the structure and function of endomucin.Animal models and experimental medicine · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Michelle E LeBlancSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Kahira L Saez-TorresSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Issahy CanoSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Zhengping HuSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Magali Saint-GeniezSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Yin-Shan NgSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Patricia A D'AmoreSchepens Eye Research Institute of Massachusetts Eye and Ear, Boston, Massachusetts, USA.
Massachusetts Eye and Ear Infirmary · USSmith-Kettlewell Eye Research Institute · USHarvard University · US

Funding

VISION RESEARCHP30EY003790 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Patricia Ann D'Amore · 1985 to 2026
$25.5M
Training Program in the Molecular Bases of Eye DiseasesT32EY007145 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI Patricia Ann D'Amore, MEREDITH GREGORY-KSANDER · 1997 to 2026
$4.5M
Investigation of endomucin as a novel regulator of angiogenesisR01EY026539 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI D'AMORE, PATRICIA ANN · 2017 to 2024
$4.1M
NEI NIH HHS P30 EY003790NEI NIH HHS R01 EY026539NEI NIH HHS T32 EY007145
6 · The paper itself

Abstract

We have previously shown that knockdown of endomucin (EMCN), an integral membrane glycocalyx glycoprotein, prevents VEGF-induced proliferation, migration, and tube formation

Indexed as

AdenoviridaeCell LineCell MovementCell ProliferationEndocytosisGlycocalyxHumansPhosphorylationSialomucinsVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2SialomucinsVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2angiogenesisendocytosisendotheliumVEGF

Identifiers

PMID31141406
PMCPMC6662976
OpenAlexW2947259603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.