Evidence map›Paper›PMID 31141314›Full record

ArticleEnvironmental toxicology2019

Antioxidant activity of Coridius chinensis extracts on manganese-induced testicular damage in rats.

Qiongyou Liu, Changhuo Cen, Huihui Fu, Fengyue Wang, Yong Wang, Tiantian Xu, Xiaohui Hou

Open access · hybridAbstract read
In one paragraph

Article in Environmental toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Heliyon · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. Counteracting effects of heavy metals and antioxidants on male fertility.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qiongyou LiuDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.
Changhuo CenDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.
Huihui FuDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.
Fengyue WangDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.
Yong WangDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.
Tiantian XuDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.
Xiaohui HouDepartment of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.ORCID https://orcid.org/0000-0002-7713-2808
Zunyi Medical University · CN

Funding

Major scientific and technological project [2014] 031Science Fund Project of Basic Medical Sciences School JC2018-4
6 · The paper itself

Abstract

Coridius chinensis (C. chinensis) is a traditional Chinese medicine that has been used to treat pain, erectile dysfunction, and other diseases. Our previous study demonstrated that manganese-induced reproductive damage was partially rescued by a medium dose of C. chinensis treatment in rat. However, the underlying mechanism is unknown. In this study, we found that the weight of reproductive organs and the sperm count in manganese-exposed rat were partially rescued by C. chinensis extracts (CcE) treatment. The number of apoptotic cells was significantly decreased and the expression of malondialdehyde, cytochrome c, and caspase-3 in manganese-exposed rats was significantly decreased after high dose of CcE treatment. Further studies revealed that the activity of superoxide dismutase, total antioxidant capacity, and glutathione peroxidase enzymes was significantly increased in testis tissues and serum of manganese-exposed rats with high dose of CcE treatment. Taken together, the results of this study suggest that CcE inhibits the Mn

Indexed as

AnimalsAntioxidantsApoptosisCaspase 3Cytochromes cGlutathione PeroxidaseHeteropteraMaleMalondialdehydeManganeseOxidative StressPlant ExtractsRatsRats, Sprague-DawleySpermatozoaSuperoxide DismutaseAntioxidantsCASP3 protein, humanCaspase 3Cytochromes cGlutathione PeroxidaseMalondialdehydeManganesePlant ExtractsSuperoxide DismutaseantioxidantapoptosisCoridius chinensis extracts (CcE)manganese

Identifiers

PMID31141314
PMCPMC6771807
OpenAlexW2947155707

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.