ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2019
Obesity and hypertension contribute to prolong QRS complex duration among middle-aged adults.
Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Assessment of Hypertension Using Clinical Electrocardiogram Features: A First-Ever Review.Frontiers in medicine · 2020Pooled it
- Identifying Demographic Factors Affecting the ECG Duration Collected Using a Single-Lead ECG Patch Device.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025Trial
- Article
- Assessment of the Cardiovascular Risk of High-Fat-High-Fructose Diet in Hereditary Hypertriacylglycerolemic Rats and Venlafaxine Effect.Physiological research · 2024Article
- The Effect of Obesity on Repolarization and Other ECG Parameters.Journal of clinical medicine · 2024Article
- Correlates of Autonomic Function, Hemodynamics, and Physical Activity Performance During Exercise Stress Testing Among Firefighters.Biological research for nursing · 2023Article
- Fibroblast growth factor 21 is associated with widening QRS complex and prolonged corrected QT interval in patients with stable angina.BMC cardiovascular disorders · 2022Article
- Electrocardiography in Hypertensive Patients without Cardiovascular Events: A Valuable Predictor Tool?International journal of hypertension · 2022Article
- Effects of cocaine and/or heroin use on resting cardiovascular function.International journal of cardiology. Cardiovascular risk and prevention · 2021Article
- Neural networks applied to 12-lead electrocardiograms predict body mass index, visceral adiposity and concurrent cardiometabolic ill-health.Cardiovascular digital health journal · 2021Article
- Occupational stress and psychological health impact on hypertension of miners in noisy environment in Wulumuqi, China: a case-control study.BMC public health · 2020Article
- Exercise-Induced Premature Ventricular Contractions Are Associated With Myocardial Ischemia Among Asymptomatic Adult Male Firefighters: Implications for Enhanced Risk Stratification.Biological research for nursing · 2020Article
- Obesity and hypertension contribute to prolong QRS complex duration among middle-aged adults.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundObesity and hypertension are comorbid diseases, which influence cardiac structure, and are associated with increased risk for cardiovascular events. The QRS duration (QRSd) reflects ventricular depolarization, and increased QRSd is associated with poor cardiovascular outcomes. QRS duration may be influenced by obesity and HTN, and reflect the increased risk factor for poor cardiovascular outcomes. The purpose of this analysis was to assess the relations between obesity, hypertension, and the interaction between them on QRSd.
methodsIn this secondary data analysis, firefighters without documented cardiovascular disease in normal sinus rhythm were included. Twelve-lead 24-hr ECG Holter monitors measured mean QRSd. Body mass index (BMI) and resting blood pressure (BP) were measured and categorized. Univariate linear regression models were produced using BMI, BP, and the interaction between BMI and BP as factors associated with QRSd. Multivariate models adjusting for multiple covariates were also produced.
resultsSeventy-seven firefighters were included and most (89.4%) were overweight or obese. After covariate adjustment, BMI (p = 0.028), BMI categorization (p = 0.020), and the interaction between BMI and systolic BP (p = 0.021) were associated with prolong QRSd.
conclusionsIncreased BMI and an interaction between BMI and systolic BP were independently associated with prolongation of the QRS complex. Determination of the underlying cardiac structures responsible prolongation of the QRSd is recommended for further research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.