Evidence map›Paper›PMID 31141183›Full record

ArticleAlcoholism, clinical and experimental research2019

A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults.

Grace Chan, John R Kramer, Marc A Schuckit, Victor Hesselbrock, Kathleen K Bucholz, Howard J Edenberg, Laura Acion, Douglas Langbehn, Vivia McCutcheon, John I Nurnberger and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Alcoholism, clinical and experimental research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Grace ChanFrom the, University of Connecticut, (GC, VH, MH), Farmington, Connecticut.ORCID 0000-0002-1257-6889
John R KramerDepartment of Psychiatry, (JRK, LA, DL, BCM, AC, SK), University of Iowa Carver College of Medicine, Iowa City, Iowa.ORCID 0000-0002-1321-7087
Marc A SchuckitUniversity of California, San Diego, (MAS), La Jolla, California.ORCID 0000-0002-2323-7858
Victor HesselbrockFrom the, University of Connecticut, (GC, VH, MH), Farmington, Connecticut.ORCID 0000-0002-0495-8641
Kathleen K BucholzWashington University, (KKB, VM, LB), St. Louis, Missouri.
Howard J EdenbergIndiana University, (HJE, JIN), Indianapolis, Indiana.ORCID 0000-0003-0344-9690
Laura AcionDepartment of Psychiatry, (JRK, LA, DL, BCM, AC, SK), University of Iowa Carver College of Medicine, Iowa City, Iowa.
Douglas LangbehnDepartment of Psychiatry, (JRK, LA, DL, BCM, AC, SK), University of Iowa Carver College of Medicine, Iowa City, Iowa.
Vivia McCutcheonWashington University, (KKB, VM, LB), St. Louis, Missouri.
John I NurnbergerIndiana University, (HJE, JIN), Indianapolis, Indiana.
Michie HesselbrockFrom the, University of Connecticut, (GC, VH, MH), Farmington, Connecticut.
Bernice PorjeszState University of New York, (BP), Brooklyn, New York.
Laura BierutWashington University, (KKB, VM, LB), St. Louis, Missouri.
Bethany C MarennaDepartment of Psychiatry, (JRK, LA, DL, BCM, AC, SK), University of Iowa Carver College of Medicine, Iowa City, Iowa.
Angella CookmanDepartment of Psychiatry, (JRK, LA, DL, BCM, AC, SK), University of Iowa Carver College of Medicine, Iowa City, Iowa.
Samuel KupermanDepartment of Psychiatry, (JRK, LA, DL, BCM, AC, SK), University of Iowa Carver College of Medicine, Iowa City, Iowa.

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JESSICA E SALVATORE · 1989 to 2026
$162.7M
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
NIAAA NIH HHS U10 AA008401NIA NIH HHS U24 AG021886
6 · The paper itself

Abstract

backgroundAlcohol consumption and problems are increasing among older adults, who are at elevated risk for alcohol-related accidents and medical problems. This paper describes a pilot follow-up of older adults with a history of alcohol dependence that was designed to determine the feasibility of conducting a more extensive investigation.

methodsThe sample consisted of previously assessed subjects in the Collaborative Studies on the Genetics of Alcoholism who: (i) were age 50+; (ii) had lifetime DSM-IV AD; and (iii) had DNA available. Individuals were located through family contacts, Internet searches, and death registries. A brief telephone interview assessed demographics, health, and alcohol involvement.

resultsOf the total sample (N = 2,174), 36% were contacted, 24% were deceased, and 40% were not yet located. Most (89%) contacted subjects were interviewed, and 99% of them agreed to future evaluation. Thirty percent of interviewed subjects reported abstinence for 10+ years, 56% reported drinking within the past year, and 14% last drank between >1 and 10 years ago. There were no age-related past-year differences in weekly consumption (overall sample mean: 16 drinks), number of drinking weeks (30.8), maximum number of drinks in 24 hours (8.1), or prevalence of weekly risky drinking (19%). Among those who drank within the past 5 years, the 3 most common alcohol-related problems were spending excessive time drinking or recovering (49%), drinking more/longer than intended (35%), and driving while intoxicated (35%); and about a third (32%) received some form of treatment.

conclusionsOver a 1-year period, we located 60% of individuals last seen an average of 23 years ago. The majority of contacted individuals were interviewed and willing to be evaluated again. Although the proportion of individuals currently drinking diminished with age, subjects exhibited troublesome levels of alcohol consumption and problems. Our findings suggest the importance and feasibility of a more comprehensive follow-up.

Indexed as

AgedAge FactorsAlcohol AbstinenceAlcohol DrinkingAlcoholismDriving Under the InfluenceFemaleFollow-Up StudiesHumansMaleMiddle AgedPilot ProjectsPrevalenceRisk-TakingUnited StatesAlcohol DependenceCOGAFollow-UpOlder Adults

Identifiers

PMID31141183
PMCPMC6685546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.