Evidence map›Paper›PMID 31140863›Full record

ArticleEpigenomics2019

Salivary microRNAs identified by small RNA sequencing and machine learning as potential biomarkers of alcohol dependence.

Andrew J Rosato, Xiaochun Chen, Yoshiaki Tanaka, Lindsay A Farrer, Henry R Kranzler, Yaira Z Nunez, David C Henderson, Joel Gelernter, Huiping Zhang

Open access · greenAbstract read
In one paragraph

Article in Epigenomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. RNA biomarkers for alcohol use disorder.Frontiers in molecular neuroscience · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. MicroRNAs and Cancer Racial Disparities.Wiley interdisciplinary reviews. RNA
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Andrew J RosatoDepartment of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA.
Xiaochun ChenDepartment of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA.
Yoshiaki TanakaDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.
Lindsay A FarrerDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.
Henry R KranzlerDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania & VISN4 MIRECC, Crescenz VAMC, Philadelphia, PA 19104, USA.
Yaira Z NunezDepartment of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.
David C HendersonDepartment of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA.
Joel GelernterDepartment of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA.
Huiping ZhangDepartment of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA.
Boston University · USGTx (United States) · USPhiladelphia VA Medical Center · USUniversity School · USVA Connecticut Healthcare System · USYale University · US

Funding

Brain microRNA-mRNA regulatory networks and alcohol use disordersR01AA025080 · NIAAA · YALE UNIVERSITY · PI ZHANG, HUIPING · 2016 to 2020
$1.7M
Salivary MicroRNAs as Biomarkers for Alcohol DependenceR21AA023068 · NIAAA · YALE UNIVERSITY · PI ZHANG, HUIPING · 2015 to 2016
$344k
NIAAA NIH HHS R01 AA025080NIAAA NIH HHS R21 AA023068
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Machine LearningAdultAlcoholismBiomarkersBlack or African AmericanCase-Control StudiesFemaleGene Expression RegulationHumansMaleMicroRNAsMiddle AgedSalivaSequence Analysis, RNAWhite PeopleBiomarkersMicroRNAsalcohol dependencedifferential expressionmachine learningsalivary microRNAsmall RNA sequencing

Identifiers

PMID31140863
PMCPMC6595542
OpenAlexW2947093867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.