Evidence map›Paper›PMID 31140825›Full record

ArticleAcupuncture in medicine : journal of the British Medical Acupuncture Society2019

Moxibustion at CV4 alleviates atherosclerotic lesions through activation of the LXRα/ABCA1 pathway in apolipoprotein-E-deficient mice.

Yingxue Cui, Juntian Liu, Chang Huang, Baixiao Zhao

Open access · hybridAbstract read
In one paragraph

Article in Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Intranasal essential oils in therapy: advances in clinical applications and delivery mechanisms.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Role of Bile Acids and Nuclear Receptors in Acupuncture in Improving Crohn's Disease.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  8. Effect of Moxibustion on Hyperhomocysteinemia and Oxidative Stress Induced by High-Methionine Diet.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yingxue Cui1 Acupuncture and Moxibustion Department, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Juntian Liu2 Acupuncture and Moxibustion Department, Huguosi Hospital of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.ORCID 0000-0002-7922-8707
Chang Huang3 School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China.
Baixiao Zhao3 School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the anti-atherogenic effect of moxibustion and whether it is mediated through the reverse cholesterol transport process.

methods8-week-old male apolipoprotein E deficient (ApoE

resultsThe moxibustion-treated (AS+M) mice showed a significantly lower plaque area percentage in the aortic root and thoracic aorta, and higher expression of LXRα and ABCA1 in the thoracic aorta compared with the AS mice. No significant differences were found in average lipid area percentage in the thoracic aorta, or ABCG1 expression in the thoracic aorta, between mice in the AS+M and AS groups.

conclusionMoxibustion treatment at CV4 suppressed the progression of atherosclerotic lesions in ApoE

Indexed as

MoxibustionAnimalsAorta, ThoracicApolipoproteins EAtherosclerosisATP Binding Cassette Transporter 1HumansLipid MetabolismLiver X ReceptorsMaleMiceMice, Inbred C57BLMice, KnockoutAbca1 protein, mouseApolipoproteins EATP Binding Cassette Transporter 1Liver X Receptorsatherosclerosischolesterol effluxlipid metabolismmoxibustionreverse cholesterol transport

Identifiers

PMID31140825
PMCPMC7433780
OpenAlexW2947745462

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.