Evidence map›Paper›PMID 31140795›Full record

ArticleJournal of the American Chemical Society2019

Synthesis of anti-1,3 Amino Alcohol Motifs via Pd(II)/SOX Catalysis with the Capacity for Stereodivergence.

Rulin Ma, Jonathon Young, Rossella Promontorio, Friederike M Dannheim, Christopher C Pattillo, M Christina White

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Catalytic Asymmetric Cycloaddition of Olefins with In Situ GeneratedJournal of the American Chemical Society · 2024
    Article
  2. Construction ofMolecules (Basel, Switzerland) · 2023
    Article
  3. Review
  4. Diastereoconvergent synthesis ofChemical science · 2022
    Article
  5. Bifunctional Polyene Cyclizations: Synthetic Studies on Pimarane Natural Products.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rulin MaRoger Adams Laboratory, Department of Chemistry , University of Illinois , Urbana , Illinois 61801 , United States.ORCID 0000-0001-9078-6315
Jonathon YoungRoger Adams Laboratory, Department of Chemistry , University of Illinois , Urbana , Illinois 61801 , United States.
Rossella PromontorioRoger Adams Laboratory, Department of Chemistry , University of Illinois , Urbana , Illinois 61801 , United States.
Friederike M DannheimRoger Adams Laboratory, Department of Chemistry , University of Illinois , Urbana , Illinois 61801 , United States.
Christopher C PattilloRoger Adams Laboratory, Department of Chemistry , University of Illinois , Urbana , Illinois 61801 , United States.ORCID 0000-0002-6353-2755
M Christina WhiteRoger Adams Laboratory, Department of Chemistry , University of Illinois , Urbana , Illinois 61801 , United States.ORCID 0000-0002-9563-2523

Funding

Selective C(sp3)-H Oxidations and Functionalizations with Tunable Metal Catalysts for SynthesisR35GM122525 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Maria Christina White · 2017 to 2026
$5.3M
NIGMS NIH HHS R35 GM122525
6 · The paper itself

Abstract

We report the development of a Pd(II)/(±)-MeO-SOX/2,5-dimethylbenzoquinone system that enables unprecedented access to anti-1,3 amino alcohol motifs in good yields (33 substrates, avg. 66% isolated yield, >20:1 dr) and high selectivities (avg. 10:1 dr). Switching ligands to (±)-CF

Indexed as

AlkenesAmino AlcoholsBenzoquinonesCatalysisOrganoplatinum CompoundsOxazinesStereoisomerismSulfoxidesAlkenesAmino AlcoholsBenzoquinonesOrganoplatinum CompoundsOxazinesSulfoxides

Identifiers

PMID31140795
PMCPMC7043790

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.