Evidence map›Paper›PMID 31140569›Full record

Trial reportThe journals of gerontology. Series B, Psychological sciences and social sciences2020

Home-Based, Adaptive Cognitive Training for Cognitively Normal Older adults: Initial Efficacy Trial.

Hyun Kyu Lee, James D Kent, Christopher Wendel, Fredric D Wolinsky, Eric D Foster, Michael M Merzenich, Michelle W Voss

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The journals of gerontology. Series B, Psychological sciences and social sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. The Effects of Computerized Cognitive Training in Older Adults' Cognitive Performance and Biomarkers of Structural Brain Aging.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Trial
  6. Trial
  7. Trial
  8. Trial
  9. Comparing Web-Based and Classroom-Based Memory Training for Older Adults: The ACTIVE Memory Works™ Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2020
    Trial
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Educational Attainment Moderates Task-State Control Network Connectivity Relations to Response Conflict Among Healthy Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  18. Article
  19. Applying the Health Belief Model to Quantify and Investigate Expectations for Computerized Cognitive Training.Journal of cognitive enhancement : towards the integration of theory and practice · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyun Kyu LeeDepartment of Research and Development, Posit Science Inc., San Francisco, California.
James D KentInterdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa.
Christopher WendelDepartment of Psychological and Brain Sciences, University of Iowa, Iowa.
Fredric D WolinskyDepartment of Health Management and Policy, College of Public Health, University of Iowa, Iowa.
Eric D FosterDepartment of Biostatistics, College of Public Health, University of Iowa, Iowa.
Michael M MerzenichDepartment of Research and Development, Posit Science Inc., San Francisco, California.
Michelle W VossInterdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa.

Funding

Plasticity-based Adaptive Cognitive Remediation for Alzheimers Disease Phase IIR44AG047722 · NIA · POSIT SCIENCE CORPORATION · PI LEE, HYUN KYU · 2017 to 2025
$4.6M
Plasticity-based Adaptive Cognitive Remediation for Alzheimer DiseaseR43AG047722 · NIA · POSIT SCIENCE CORPORATION · PI LEE, HYUN KYU · 2014 to 2015
$698k
NIA NIH HHS R43 AG047722NIA NIH HHS R44 AG047722
6 · The paper itself

Abstract

objectivesWe examined whether a home-based, adaptive cognitive training (CT) program would lead to cognitive performance changes on a neuropsychological test battery in cognitively normal older adults.

methodSixty-eight older adults (age = 70.0, SD = 3.74) were randomly assigned to either CT or an active control group (AC, casual computer games). Participants were instructed to train on their assigned programs for 42 min per day, 5 days per week, over 10 weeks (35 hr of total program usage). Participants completed tests of processing speed, working memory, and executive control before and after 10 weeks of training.

resultsTraining groups did not differ in performance before training. After training, CT participants out-performed AC participants in the overall cognitive composite score, driven by processing speed and working memory domains. DISCUSSION: Our results show that a limited dose of home-based CT can drive cognitive improvements as measured with neuropsychological test battery, suggesting potential cognitive health maintenance implications for cognitively normal older adults.

Indexed as

CognitionExecutive FunctionHome Care ServicesInternet-Based InterventionMemory, Short-TermNeuropsychological TestsAgedCognitive Behavioral TherapyCognitive DysfunctionFemaleHumansMaleMental ProcessesOutcome Assessment, Health CareVideo GamesCognitive improvementCognitively normalNeuropsychological test battery

Identifiers

PMID31140569
PMCPMC7265807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.