Evidence map›Paper›PMID 31140425›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Expression of NUF2 in breast cancer and its clinical significance].

Jingbo Sun, Jiawei Chen, Zhizhi Wang, Yunyao Deng, Lixin Liu, Xiaolong Liu

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. NUF2 Promotes Breast Cancer Development as a New Tumor Stem Cell Indicator.International journal of molecular sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jingbo SunDepartment of General Surgery, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Jiawei ChenSouthern Medical University, Guangzhou 510515, China.
Zhizhi WangSouthern Medical University, Guangzhou 510515, China.
Yunyao DengDepartment of General Surgery, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Lixin LiuDepartment of General Surgery, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Xiaolong LiuDepartment of General Surgery, Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China.
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the expression of the cell division- associated gene NUF2 in breast cancer and its clinical significance.

methodsThe expression of NUF2 in breast cancer tissues was analyzed using Oncomine database. The relationship between the expression of NUF2 and the prognosis of breast cancer was analyzed using the Kaplan-Meier Plotter database. Gene set enrichment analysis (GSEA) and GEO database were used to investigate the effect of NUF2 on gene enrichment. The String database was utilized to analyze the proteins associated with NUF2. The TIMER database was analyzed to assess the correlations of NUF2 with BUB1, MAD2L1 and MYC. The expressions of NUF2 mRNA in 8 pairs of breast cancer tissues and adjacent tissues were verified by q-PCR.

resultsCompared with that in normal breast tissue, NUF2 was significantly overexpressed in breast cancer (

conclusionsNUF2 gene is overexpressed in breast cancer, and its expression level is important in predicting the prognosis of breast cancer.

Indexed as

Breast NeoplasmsCell Cycle ProteinsGene Expression Regulation, NeoplasticHumansPhosphatidylinositol 3-KinasesPrognosisCell Cycle ProteinsNUF2 protein, humanPhosphatidylinositol 3-Kinasesbreast cancerdatabase analysisNUF2prognosis

Identifiers

PMID31140425
PMCPMC6743945
OpenAlexW2997594819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.