Evidence map›Paper›PMID 31140421›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Mig-

Fan Wang, Fenglong Chen, Weipeng Hu, Yi Zhang

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. [Effects of RNA interference of CTHRC1 on proliferation and apoptosis of thyroid papillary cancer TCP-1 cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fan WangDepartment of Neurosurgery, Third Hospital of Xiamen, Xiamen 361100, China.
Fenglong ChenDepartment of Neurosurgery, Third Hospital of Xiamen, Xiamen 361100, China.
Weipeng HuDepartment of Neurosurgery, Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China.
Yi ZhangDepartment of Neurosurgery, Third Hospital of Xiamen, Xiamen 361100, China.
Second Affiliated Hospital of Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the inhibitory effects of silencing migration-inducing gene-7 (Mig-7) on vasculogenic mimicry formation, migration and invasion of human glioma cells

methodsHuman glioma U251 cells were infected by lentiviral vectors carrying a small interfering RNA targeting Mig-7 gene (sh-Mig-

resultsWe successfully obtained a U251 cell line with stable low expression of Mig-

conclusionsSilencing of Mig-7 gene inhibits vasculogenic mimicry formation and invasion of U251 cells possibly by suppressing MEK/ERK signaling, suggesting the important role of Mig-7 gene in vasculogenic mimicry formation and invasion of human glioma cells.

Indexed as

Gene SilencingGliomaNeoplasm ProteinsCell Line, TumorCell MovementCell ProliferationHumansRNA, Small InterferingSignal TransductionNeoplasm ProteinsRNA, Small InterferingTOX4 protein, humangliomaMig-7RNA interferencetumor invasionvasculogenic mimicry

Identifiers

PMID31140421
PMCPMC6743935
OpenAlexW2953472790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.