Evidence map›Paper›PMID 31140331›Full record

ArticleImmunotherapy2019

Long-term survival and differentiation of human thymocytes in human thymus-grafted immunodeficient mice.

Yang Tang, Yong-Guang Yang, Ou Bai, Jinxing Xia, Zheng Hu

Open access · greenAbstract read
In one paragraph

Article in Immunotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Patient-Derived Xenograft Models in Cervical Cancer: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  2. Pooled it
  3. Review
  4. Humanized mouse models for immuno-oncology research.Nature reviews. Clinical oncology · 2023
    Review
  5. Review
  6. Thymus Regeneration and Future Challenges.Stem cell reviews and reports · 2020
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Yang TangKey Laboratory of Organ Regeneration & Transplantation of Ministry of Education, The First Hospital of Jilin University, Changchun, 130061, PR China.
Yong-Guang YangColumbia Center for Translational Immunology, Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
Ou BaiKey Laboratory of Organ Regeneration & Transplantation of Ministry of Education, The First Hospital of Jilin University, Changchun, 130061, PR China.
Jinxing XiaColumbia Center for Translational Immunology, Department of Medicine, Columbia University College of Physicians & Surgeons, New York, NY 10032, USA.
Zheng HuKey Laboratory of Organ Regeneration & Transplantation of Ministry of Education, The First Hospital of Jilin University, Changchun, 130061, PR China.ORCID 0000-0001-8310-4224
Jilin University · CNAnhui Medical University · CNColumbia University · US

Funding

Immune response to allogeneic hESC-derived endothelial cells RC1HL100117 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI YANG, YONG-GUANG · 2010 to 2010
$895k
NHLBI NIH HHS RC1 HL100117
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Organ TransplantationThymocytesThymus GlandAnimalsCell SurvivalHeterograftsLymphopoiesisMiceMice, Inbred NODTime Factorshumanhumanized mouseT-cell developmentthymopoiesisthymus

Identifiers

PMID31140331
PMCPMC6949514
OpenAlexW2946929626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.