Evidence map›Paper›PMID 31140267›Full record

ArticleACS infectious diseases2019

Targeting Mobilization of Ferrous Iron in

Brian R Blank, Poulami Talukder, Ryan K Muir, Erin R Green, Eric P Skaar, Adam R Renslo

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Ferrous Iron-Dependent Pharmacology.Trends in pharmacological sciences · 2021
    Review
  7. Review
  8. Iron Acquisition by Bacterial Pathogens: Beyond Tris-Catecholate Complexes.Chembiochem : a European journal of chemical biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Brian R BlankDepartment of Pharmaceutical Chemistry , University of California, San Francisco , 600 16th Street , San Francisco , California 94158 , United States.
Poulami TalukderDepartment of Pharmaceutical Chemistry , University of California, San Francisco , 600 16th Street , San Francisco , California 94158 , United States.
Ryan K MuirDepartment of Pharmaceutical Chemistry , University of California, San Francisco , 600 16th Street , San Francisco , California 94158 , United States.
Erin R GreenDepartment of Pathology, Microbiology, and Immunology , Vanderbilt University Medical Center , 1161 21st Avenue South, Medical Center North , Nashville , Tennessee 37232 , United States.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology , Vanderbilt University Medical Center , 1161 21st Avenue South, Medical Center North , Nashville , Tennessee 37232 , United States.
Adam R RensloDepartment of Pharmaceutical Chemistry , University of California, San Francisco , 600 16th Street , San Francisco , California 94158 , United States.ORCID 0000-0002-1240-2846
University of California, San Francisco · USVanderbilt University Medical Center · US

Funding

Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
RESEARCH TRAINING IN CHEMISTRY AND CHEMICAL BIOLOGYT32GM064337 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIK, CHARLES SCOTT · 2002 to 2021
$7.8M
Interdisciplinary Training Program in Lung ResearchT32HL094296 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ray Stokes Peebles · 2008 to 2026
$6.3M
Chemical Methods for Ferrous Iron Dependent Drug DeliveryR01AI105106 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RENSLO, ADAM R · 2013 to 2022
$4.6M
NHLBI NIH HHS T32 HL094296NIAID NIH HHS R01 AI101171NIAID NIH HHS R01 AI105106NIGMS NIH HHS T32 GM064337
6 · The paper itself

Abstract

Iron is essential to all life, and competition for this vital nutrient is central to host-pathogen interactions during infection. The opportunistic Gram-negative pathogen

Indexed as

AmidohydrolasesAnimalsAnti-Bacterial AgentsEnzyme InhibitorsFemaleFerrous CompoundsGram-Negative BacteriaHost-Pathogen InteractionsHydroxamic AcidsLungMiceProdrugsPseudomonas aeruginosaRespiratory Tract InfectionsAmidohydrolasesAnti-Bacterial AgentsEnzyme InhibitorsFerrous CompoundsHydroxamic AcidsLpxC deacetylase, PseudomonasProdrugscaged antibioticshost−pathogen interactioniron acquisitionnutrient acquisitiontargeted prodrugstissue targeting

Identifiers

PMID31140267
PMCPMC6880962
OpenAlexW2946959937

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.