Evidence map›Paper›PMID 31140130›Full record

ArticleJournal of neurovirology2019

Diffuse large B cell lymphoma secondary to JC virus in progressive multifocal leukoencephalopathy.

Ashwin Reddi, Nikhil Patel, Nicholas A Morris

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In one paragraph

Article in Journal of neurovirology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ashwin ReddiSchool of Medicine, University of Maryland, Baltimore, MD, USA.ORCID 0000-0002-4830-4172
Nikhil PatelDivision of Neurocritical Care and Emergency Neurology, University of Maryland, School of Medicine, 22 South Greene Street, Baltimore, MD, 20201, USA.
Nicholas A MorrisDivision of Neurocritical Care and Emergency Neurology, University of Maryland, School of Medicine, 22 South Greene Street, Baltimore, MD, 20201, USA. nicholas.morris@som.umaryland.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 43-year-old-man with a past medical history of HIV with recently initiated HAART and existing PML that presented with altered mental status. The initial diagnosis was deemed to be PML-IRIS; however, neuroimaging brought into question this diagnosis. Flow cytometry performed from the cerebrospinal fluid revealed diffuse large B cell lymphoma. JC virus may act in an oncogenic role similarly to EBV and predispose to CNS lymphomas. Patients with PML caused by JC virus may develop secondary malignancies.

Indexed as

AdultAntiretroviral Therapy, Highly ActiveHIV InfectionsHumansJC VirusLeukoencephalopathy, Progressive MultifocalLymphoma, Large B-Cell, DiffuseMaleDiffuse large B cell lymphomaEBVIRISJC virusMalignancyPML

Identifiers

PMID31140130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.