Evidence map›Paper›PMID 31140127›Full record

ArticleJournal of fluorescence2019

Analysis of Bisulfite Via a Nitro Derivative of Cyanine-3 (NCy3) in the Microfluidic Channel.

Haley A Houtwed, Meng Xie, Aatiya Ahmad, Cody D Masters, Melissa M Davison, Kristy Kounovsky-Shafer, Haishi Cao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fluorescence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haley A HoutwedDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
Meng XieDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
Aatiya AhmadDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
Cody D MastersDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
Melissa M DavisonDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
Kristy Kounovsky-ShaferDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA.
Haishi CaoDepartment of Chemistry, University of Nebraska-Kearney, Kearney, NE, 68849, USA. Caoh1@unk.edu.

Funding

UNMC Structural Biology CoreP20GM103427 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Heather Colleen Jensen-Smith · 2012 to 2026
$59.2M
ZINC FINGER-INSPIRED FLUORESCENT CHEMOSENSORSP20RR016469 · NCRR · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI TURPEN, JAMES B · 2001 to 2011
$36.2M
National Center for Research Resources NCRR; 5P20RR016469National Institute of General Medical Sciences NIGMS; INBRE-8P20GM103427NCRR NIH HHS P20 RR016469NIGMS NIH HHS P20 GM103427
6 · The paper itself

Abstract

NCy3, a derivative of Cyanine 3 with a nitro substituent, showed a high reactivity to bisulfite in aqueous media, instantly leading to ratiometric change of absorption spectra and significant fluorescence quenching. Applied in the microfluidic channel, NCy3 functionalize as a sensitive approach for quantitative detection of bisulfite, particularly for samples with a small volume.

Indexed as

Bisulfite sensorCyanine dyeMicrofluidic channelNitration

Identifiers

PMID31140127
PMCPMC6612305

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.