ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2019
Acute upper gastrointestinal bleed: An audit of the causes and outcomes from a tertiary care center in eastern India.
Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Comprehensive review on the current management of upper-GI bleed.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Review
- Comparison of risk assessment scores of upper gastrointestinal bleeding: Proposal for a simplified score.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Article
- A portal into hemodynamics: utility of portal vein ultrasound in predicting variceal etiology of upper gastrointestinal hemorrhage in the emergency department.Internal and emergency medicine · 2025Article
- Etiology and Short-Term Outcomes of Upper Gastrointestinal Bleeding in Patients Presenting at the Emergency Department in a Tertiary Hospital in a Low Resource Setting-A Prospective Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Thrombocytopenia and Grading of Esophageal Varices in Patients With Chronic Liver Disease.Cureus · 2024Article
- Endoscopic Findings in Patients With Upper Gastrointestinal Bleeding in Ogun State, Nigeria.Cureus · 2022Article
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
background/purpose of the studyAcute upper gastrointestinal (UGI) bleed is a life-threatening emergency carrying risks of rebleed and mortality despite standard pharmacological and endoscopic management. We aimed to determine etiologies of acute UGI bleed in hospitalized patients and outcomes (rebleed rates, 5-day mortality, in-hospital mortality, 6-week mortality, need for surgery) and to determine predictors of rebleed and mortality.
methodsClinical and endoscopic findings were recorded in patients aged > 12 years who presented within 72 h of onset of UGI bleed. Outcomes were recorded during the hospital stay and 6 weeks after discharge.
resultsA total of 305 patients were included in this study, mean age being 44 ± 17 years. Most common etiology of UGI bleed was portal hypertension (62.3%) followed by peptic ulcer disease (PUD) (16.7%). Rebleed rate within 6 weeks was 37.4% (portal hypertension 47.9%, PUD 21.6%, malignancy 71.4%). Five-day mortality was 2.3% (malignancy 14.3%, portal hypertension 3.2%); the in-hospital mortality rate was 3.0% (malignancy 14.3%, portal hypertension 3.2%, PUD 0.0%) and 4.9% at 6 weeks (malignancy 28.6%, portal hypertension 5.8%, PUD 0.0%). Surgery was required in 4.59% patients. On multivariate analysis, post-endoscopy Rockall score was significantly predictive of rebleed in both portal hypertension- and PUD-related rebleed. No factors were found predictive of mortality in multivariate analysis.
conclusionPortal hypertension remains the commonest cause of UGI bleed in India and carries a higher risk of rebleed and mortality as compared to PUD-related bleed. Post-endoscopy Rockall score is a useful tool for clinicians to assess risk of rebleed.
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