Evidence map›Paper›PMID 31140002›Full record

Trial reportSurgical endoscopy2020

Endoscopic versus laparoscopic drainage of pseudocyst and walled-off necrosis following acute pancreatitis: a randomized trial.

Pramod Kumar Garg, Danishwar Meena, Divya Babu, Rajesh Kumar Padhan, Rajan Dhingra, Asuri Krishna, Subodh Kumar, Mahesh Chandra Misra, Virinder Kumar Bansal

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 6 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 6 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Guideline
  2. Pooled it
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  7. Review
  8. Review
  9. Article
  10. Article
  11. Pancreatic pseudocyst: The past, the present, and the future.World journal of gastrointestinal surgery · 2024
    Review
  12. Infected pancreatic necrosis-Current trends in management.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  13. Minimally invasive surgery compared to endoscopic intervention for treating infected pancreatic necrosis. A meta-analysis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Article
  14. Review
  15. The Association of Polish Surgeons (APS) clinical guidelines for the use of laparoscopy in the management of abdominal emergencies. Part I.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pramod Kumar GargDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India. pkgarg@aiims.ac.in.
Danishwar MeenaDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Divya BabuDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Rajesh Kumar PadhanDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Rajan DhingraDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
Asuri KrishnaDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Subodh KumarDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Mahesh Chandra MisraDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Virinder Kumar BansalDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India. drvkbansal@gmail.com.
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic fluid collections (PFC) may develop following acute pancreatitis (AP). Endoscopic and laparoscopic internal drainage are accepted modalities for drainage of PFCs but have not been compared in a randomized trial. Our objective was to compare endoscopic and laparoscopic internal drainage of pseudocyst/walled-off necrosis following AP. PATIENTS AND

methodsPatients with symptomatic pseudocysts or walled-off necrosis suitable for laparoscopic and endoscopic transmural internal drainage were randomized to either modality in a randomized controlled trial. Endoscopic drainage comprised of per-oral transluminal cystogastrostomy. Additionally, endoscopic lavage and necrosectomy were done following a step-up approach for infected collections. Surgical laparoscopic cystogastrostomy was done for drainage, lavage, and necrosectomy. Primary outcome was resolution of PFCs by the intended modality and secondary outcome was complications.

resultsSixty patients were randomized, 30 each to laparoscopic and endoscopic drainage. Both groups were comparable for baseline characteristics. The initial success rate was 83.3% in the laparoscopic and 76.6% in the endoscopic group (p = 0.7) after the index intervention. The overall success rate of 93.3% (28/30) and 90% (27/30) in the laparoscopic and endoscopic groups respectively was also similar (p = 1.0). Two patients in the laparoscopic group required endoscopic cystogastrostomy for persistent collections. Similarly, two patients in the endoscopic group required laparoscopic drainage. Postoperative complications were comparable between the groups except for higher post-procedure infection in the endoscopic group (19 vs. 9; p = 0.01) requiring endoscopic re-intervention.

conclusionsEndoscopic and laparoscopic techniques have similar efficacy for internal drainage of suitable pancreatic fluid collections with < 30% debris. The choice of procedure should depend on available expertise and patient preference.

Indexed as

Endoscopy, Digestive SystemLaparoscopyAdolescentAdultAgedDrainageFemaleHumansMaleMiddle AgedNecrosisPancreasPancreatic JuicePancreatic PseudocystPancreatitisPostoperative ComplicationsCystogastrostomyEndoscopicLaparoscopicPancreatic fluid collectionsPseudocystWalled off necrosis

Identifiers

PMID31140002
OpenAlexW2947209825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.