Evidence map›Paper›PMID 31139995›Full record

Trial reportSurgical endoscopy2020

Anti-reflux mucosectomy using a cap-assisted endoscopic mucosal resection method for refractory gastroesophageal disease: a prospective feasibility study.

In Kyung Yoo, Weon Jin Ko, Hak Su Kim, Hee Kyung Kim, Jung Hyun Kim, Won Hee Kim, Sung Pyo Hong, Abdullah Özgür Yeniova, Joo Young Cho

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 72 citations in OpenAlex.

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  19. Clinical efficacy of endoscopic antireflux mucosectomyAnnals of translational medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

In Kyung YooDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Weon Jin KoDepartment of Internal Medicine, Inha Universitiy College of Medicine, Incheon, Korea.
Hak Su KimDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Hee Kyung KimDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Jung Hyun KimDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Won Hee KimDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Sung Pyo HongDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Abdullah Özgür YeniovaDepartment of Gastroenterology, Tokat Gaziosmanpasa University, Tokat, Turkey.
Joo Young ChoDepartment of Gastroenterology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. cjy6695@dreamwiz.com.ORCID 0000-0001-9085-0313
CHA University Bundang Medical Center · KRInha University · KRTokat Gaziosmanpaşa Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEndoscopic therapy of gastroesophageal reflux disease (GERD) overcomes the "treatment gap" for patients with refractory GERD, who are not willing to go into surgery. We propose an easy and efficient technique that is referred to as anti-reflux mucosectomy (ARMS) using cap-assisted endoscopic mucosal resection (EMR-C) which could be called ARMS-C. This study aimed to investigate the short-term outcomes of ARMS-C in GERD patients.

methodsFrom December 2016 to February 2018, we performed ARMS-C in 33 patients with pathologic reflux disease and esophageal hypersensitivity. ARMS-C involved endoscopic mucosal resection at the circumference of the esophagogastric junction (EGJ), resulting in narrowing of the hiatal opening after healing. The GERD symptoms, 24-h pH monitoring results, manometry, endoscopy, and EGJ distensibility were compared before and after the procedure.

resultsSix months after ARMS-C, 63% of patients discontinued the use of pump inhibitors (PPIs), while 30% patients reduced their PPI dose. The GERD questionnaire scores significantly decreased after ARMS-C, from 11.0 to 6.0 (P < 0.001). The median DeMeester score and acid exposure time based on pH monitoring also improved after ARMS-C. Furthermore, the median flap valve grade and EGJ distensibility decreased from 3.0 to 1.0 (P < 0.001) and from 19.0 to 13.9 (P < 0.001), respectively. Two patients were treated with balloon dilation due to stricture, but no other serious adverse events were encountered.

conclusionARMS-C may be an effective and safe treatment method for GERD in terms of short-term outcomes.

Indexed as

Endoscopic Mucosal ResectionEsophagogastric JunctionFeasibility StudiesFemaleGastroesophageal RefluxHumansMaleMiddle AgedProspective StudiesSurveys and QuestionnairesTreatment OutcomeAnti-reflux mucosectomyCap-assisted endoscopic mucosal resectionGastroesophageal reflux diseaseShort-term outcomes

Identifiers

PMID31139995
OpenAlexW2946997362

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.