Trial reportSurgical endoscopy2020
Laparoscopic versus open appendectomy for perforated appendicitis in adults: randomized clinical trial.
Trial report in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Laparoscopic appendectomy versus antibiotic treatment for acute appendicitis-a systematic review.International journal of colorectal disease · 2021Pooled it
- Prophylactic abdominal drainage versus no drainage after laparoscopic appendectomy for perforated acute appendicitis: a multicenter propensity score-weighted analysis.Surgical endoscopy · 2026Article
- Endoscopic retrograde appendicitis therapy: Progress in clinical application.World journal of gastrointestinal endoscopy · 2026Review
- Evolving Surgical Approaches to Adult Perforated Appendicitis: A Systematic Narrative Review.Cureus · 2025Review
- Laparoscopic appendectomy improves outcomes and reduces costs in rural Kenya.Surgical endoscopy · 2025Article
- The contemporary management of perforated appendicitis in adults: To operate or wait?Surgery open science · 2024Article
- Early versus delayed appendicectomy for appendiceal phlegmon or abscess.The Cochrane database of systematic reviews · 2024Review
- Conventional herniorrhaphy followed by laparoscopic appendectomy for a variant of Amyand's hernia: a case report.Journal of medical case reports · 2024Article
- Evaluation of the Appropriate LigaSure™ Device to Transect the Appendix-A Comparison between 5 mm and 10 mm Laparoscopic Devices in an Ex Vivo Trial.Medicina (Kaunas, Lithuania) · 2023Article
- Clinical outcomes of locking polymeric clip for laparoscopic appendectomy in patients with appendicitis: a retrospective comparison with loop ligature.Annals of coloproctology · 2022Article
- Partial cecum resection using endostapler in acute complicated appendicitis with appendiceal base necrosis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Article
- Relationship Between Appendectomy Incidence and Computed Tomography Scans Based on Korean Nationwide Data, 2003-2017.Journal of Korean medical science · 2022Article
- Laparoscopic Ovariectomy in a Domestic Yak.Case reports in veterinary medicine · 2020Article
- Perforated appendicitis treated with laparoscopic appendicectomy or open appendicectomy: A meta-analysis.Journal of minimal access surgeryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe advantages of laparoscopic appendectomy did not meet the same acceptance in the setting of perforated appendicitis as in uncomplicated appendicitis in the general surgical community. The aim of this study was to compare the clinical outcome of laparoscopic and open appendectomy in perforating appendicitis.
methodsA randomized controlled study was conducted on 126 patients presenting with perforated appendicitis. Sixty patients were subjected to laparoscopic appendectomy (LA) and 66 patients underwent traditional open appendectomy (OA).
results65 (51.6%) patients were female, and 61 (48.4%) patients were male in whom the mean age was 37.6 + 8.5 years. A significant difference was calculated in the domains of postoperative pain, less need for analgesics, hospital stay, and return to daily activities. The mean operative time was shorter in OA 94 ± 10.4 min than LA 120.6 ± 17.7 min. No statistically significant difference between both groups was detected as regard occurrence of intra-abdominal collection.
conclusionIn view of its clinical outcomes, laparoscopy should be considered in the context of perforated appendicitis. The possibility of intra-abdominal collection should not be a barrier against the widespread practice of this surgical procedure amidst laparoscopic surgeons if adequate precautions are employed.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.