Evidence map›Paper›PMID 31139715›Full record

ArticleACS central science2019

Rapid Detection of

Lukas Zeininger, Sara Nagelberg, Kent S Harvey, Suchol Savagatrup, Myles B Herbert, Kosuke Yoshinaga, Joseph A Capobianco, Mathias Kolle, Timothy M Swager

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Review
  3. Carbohydrate-based biosensors for enhanced pathogen detection.Analytical and bioanalytical chemistry · 2026
    Review
  4. Self-Assembled Nanostructured Microgels with Reconfigurable Morphologies.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Lithography-free directional control of thermal emission.Nanophotonics (Berlin, Germany) · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Non-Covalent Postfunctionalization of Dye Layers on TiOChemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Fluorescent Janus emulsions for biosensing ofProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lukas ZeiningerDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Sara NagelbergDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Kent S HarveyDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Suchol SavagatrupDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Myles B HerbertDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Kosuke YoshinagaDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Joseph A CapobiancoAgricultural Research Service, United States Department of Agriculture, Wyndmoor, Pennsylvania, United States.
Mathias KolleDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Timothy M SwagerDepartment of Chemistry and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
Massachusetts Institute of Technology · USAgricultural Research Service · US

Funding

Radicals and Polyradicals for Dynamic Nuclear PolarizationR01GM095843 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SWAGER, TIMOTHY M · 2011 to 2018
$2.5M
NIGMS NIH HHS R01 GM095843
6 · The paper itself

Abstract

Reliable early-stage detection of foodborne pathogens is a global public health challenge that requires new and improved sensing strategies. Here, we demonstrate that dynamically reconfigurable fluorescent double emulsions can function as highly responsive optical sensors for the rapid detection of carbohydrates fructose, glucose, mannose, and mannan, which are involved in many biological and pathogenic phenomena. The proposed detection strategy relies on reversible reactions between boronic acid surfactants and carbohydrates at the hydrocarbon/water interface leading to a dynamic reconfiguration of the droplet morphology, which alters the angular distribution of the droplet's fluorescent light emission. We exploit this unique chemical-morphological-optical coupling to detect

Identifiers

PMID31139715
PMCPMC6535765
OpenAlexW2942008786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.