Evidence map›Paper›PMID 31139692›Full record

ArticleAnnals of clinical and translational neurology2019

Clinical significance of soluble adhesion molecules in anti-NMDAR encephalitis patients.

Yuewen Ding, Chengjia Yang, Zheyi Zhou, Yu Peng, Jinyu Chen, Suyue Pan, Hong Xu, Yuping Cai, Kaiyun Ou, Wei Xie and 1 more

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical and translational neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Yuewen DingDepartment of Neurology Nanfang Hospital Southern Medical University Guangzhou China.
Chengjia YangGuangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangdong Mental Health Center Guangzhou China.
Zheyi ZhouThe Second School of Clinical Medicine Southern Medical University Guangdong Province China.
Yu PengDepartment of Neurology Nanfang Hospital Southern Medical University Guangzhou China.
Jinyu ChenDepartment of Neurology Nanfang Hospital Southern Medical University Guangzhou China.
Suyue PanDepartment of Neurology Nanfang Hospital Southern Medical University Guangzhou China.
Hong XuThe Second School of Clinical Medicine Southern Medical University Guangdong Province China.
Yuping CaiHexian Memorial Hospital Guangzhou China.
Kaiyun OuDepartment of Neurology Laibin People's Hospital Laibin China.
Wei XieSchool of Traditional Chinese Medicine Southern Medical University Guangzhou China.
Honghao WangDepartment of Neurology Nanfang Hospital Southern Medical University Guangzhou China.ORCID https://orcid.org/0000-0002-1215-6219
Nanfang Hospital · CNGuangdong Academy of Medical Sciences · CNLiuzhou Maternal and Child Health Hospital · CNMemorial Hospital of South Bend · USSecond People’s Hospital of Yibin · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence indicates that immune system dysfunction affects anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. This study aims to investigate the relationship between adhesion molecules and the pathophysiology in anti-NMDAR encephalitis. Soluble forms of Intercellular adhesion molecule-1 (sICAM-1), vascular adhesion molecule-1 (sVCAM-1), and L-selectin (sL-selectin), were measured in the CSF and serum of 26 participants with anti-NMDAR encephalitis, 11 patients with schizophrenia and 22 patients with noninflammatory disorders. CSF levels of sICAM-1, sVCAM-1 and sL-selectin were significantly elevated in the anti-NMDAR encephalitis group. sVCAM-1 levels were positively associated with modified Rankin scale score in anti-NMDAR encephalitis patients at the onset and 3-month follow-up.

Indexed as

AdolescentAdultAnti-N-Methyl-D-Aspartate Receptor EncephalitisCell Adhesion MoleculesE-SelectinFemaleHumansIntercellular Adhesion Molecule-1L-SelectinMaleMiddle AgedVascular Cell Adhesion Molecule-1Cell Adhesion MoleculesE-SelectinICAM1 protein, humanIntercellular Adhesion Molecule-1L-SelectinVascular Cell Adhesion Molecule-1

Identifiers

PMID31139692
PMCPMC6529932
OpenAlexW2938742840

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.