Evidence map›Paper›PMID 31139661›Full record

ArticleBioMed research international2019

APC-Cdh1 Inhibits the Proliferation and Activation of Oligodendrocyte Precursor Cells after Mechanical Stretch Injury.

Xiang Ma, Yongqing Guo, Yuehong Qi, Hongpeng Zhang, Yuhua Hao, Huaping Zhang, Xiaona Li

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiang MaDepartment of Anesthesiology, Shanxi Medical University, Taiyuan, China.ORCID 0000-0003-1133-4674
Yongqing GuoDepartment of Anesthesiology, The People's Hospital of Shanxi Medical University, Taiyuan, China.ORCID 0000-0003-1642-4900
Yuehong QiDepartment of Anesthesiology, The People's Hospital of Shanxi Medical University, Taiyuan, China.
Hongpeng ZhangDepartment of Anesthesiology, Shanxi Medical University, Taiyuan, China.
Yuhua HaoDepartment of Anesthesiology, The People's Hospital of Shanxi Medical University, Taiyuan, China.
Huaping ZhangTranslational Medicine Research Center, Shanxi Medical University, Taiyuan, China.
Xiaona LiInstitute of Applied Mechanics and Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.
Shanxi Medical University · CNTaiyuan University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of spinal cord injury (SCI) continues to increase; however, the involved mechanisms remain unclear. Anaphase promoting complex (APC) and its regulatory subunit Cdh1 play important roles in the growth, development, and repair of the central nervous system (CNS). Cdh1 is involved in the pathophysiological processes of neuronal apoptosis and astrocyte-reactive proliferation after ischemic brain injury, whereas the role played by APC-Cdh1 in the proliferation and activation of oligodendrocyte precursor cells (OPCs) after SCI remains unresolved. Using primary cultures of spinal oligodendrocyte precursor cells, we successfully established an

Indexed as

Stress, MechanicalAdenoviridaeAnaphase-Promoting Complex-CyclosomeAnimalsCdh1 ProteinsCell ProliferationGenetic VectorsInhibitor of Differentiation Protein 2Oligodendrocyte Precursor CellsRats, Sprague-DawleyS-Phase Kinase-Associated ProteinsSubstrate SpecificityAnaphase-Promoting Complex-CyclosomeCdh1 ProteinsInhibitor of Differentiation Protein 2S-Phase Kinase-Associated Proteins

Identifiers

PMID31139661
PMCPMC6500630
OpenAlexW2937589279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.