Evidence map›Paper›PMID 31139587›Full record

ArticleEuropean journal of case reports in internal medicine2019

Olmesartan-Associated Enteropathy: An Unexpected Cause of Chronic Diarrhoea.

Mónica Teixeira, Sara Macedo, Ana Martins, Tânia Batista, António Novais, Maria Costa, Eugénia Cancela

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Olmesartan-Induced Enteropathy: A Case of Recurrent Diarrhoea.European journal of case reports in internal medicine · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mónica TeixeiraDepartment of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Sara MacedoDepartment of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Ana MartinsDepartment of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Tânia BatistaDepartment of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
António NovaisDepartment of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Maria CostaDepartment of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Eugénia CancelaGastroenterology Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.
Centro Hospitalar Tondela-Viseu · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olmesartan-associated enteropathy is a rare cause of severe enteropathy that should be considered in the differential diagnosis of patients with unexplained chronic diarrhoea. It may be difficult to recognise because of its clinical and histologic similarities to other clinical entities. The authors present the case of a 72-year-old woman with a 6-month clinical history of non-bloody diarrhoea and weight loss. Discontinuation of olmesartan resulted in clinical and histologic recovery, and therefore, physicians need to be aware of olmesartan-associated enteropathy in order to avoid unnecessary testing. Although rare, it is considered an emerging and underdiagnosed enteropathy. LEARNING POINTS: Olmesartan-associated enteropathy is characterised by chronic diarrhoea (often severe) and weight loss that is unresponsive to a gluten-free diet.When a patient presents with unexplained chronic diarrhoea, a detailed medication review is needed. If duodenal biopsies reveal villous atrophy and coeliac disease is excluded, drug-induced enteropathy is likely.Clinical response and histologic improvement are expected after olmesartan is withdrawn.

Indexed as

diarrhoeaenteropathyOlmesartan

Identifiers

PMID31139587
PMCPMC6499092
OpenAlexW2942506639

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.