ArticleWorld journal of diabetes2019
Association of hypoglycaemia in screening oral glucose tolerance test in pregnancy with low birth weight fetus.
Article in World journal of diabetes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04144595 (Association Between Low Plasma Glucose After Oral Glucose Tolerance Test in Pregnancy With Impaired Fetal Growth), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Association Between Low Plasma Glucose After Oral Glucose Tolerance Test in Pregnancy With Impaired Fetal Growth
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Gestational reactive hypoglycaemia and adverse pregnancy outcomes: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Perinatal Outcomes After Sleeve Gastrectomy Compared to a Matched Control Group.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Impact of Metabolic Surgery on Gestational Diabetes Mellitus: A Cohort Analysis.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- An Observational Study of Maternal Hypoglycemia in Pregnancy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Association between lower fasting plasma glucose levels during oral glucose tolerance test and adverse perinatal outcomes: A Chinese cohort study.PLoS medicine · 2025Article
- Glucose Homeostasis, Metabolomics, and Pregnancy Outcomes After Bariatric Surgery (GLORIA): Protocol for a Multicentre Prospective Cohort Study.Journal of clinical medicine · 2025Article
- Preconception hypoglycemia and adverse pregnancy outcomes in Chinese women aged 20-49 years: A retrospective cohort study in China.PLoS medicine · 2025Article
- The Lack of a Glucose Peak During the Oral Glucose Tolerance Test in Pregnancy: What Does It Portend for Perinatal Outcomes?Nutrients · 2025Article
- Association of gestational diabetes mellitus diagnosed at different time points in oral glucose tolerance test with adverse pregnancy outcomes: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- Hypoglycaemia in screening oral glucose tolerance test in pregnancy with low birth weight fetus.World journal of experimental medicine · 2024Article
- Article
- Stillbirth: prevention and supportive bereavement care.BMJ medicine · 2023Review
- Normal glucose tolerant women with low glycemia during the oral glucose tolerance test have a higher risk to deliver a low birth weight infant.Frontiers in endocrinology · 2023Article
- Reactive hypoglycaemia during the OGTT after gestational diabetes mellitus: Metabolic implications and evolution.Diabetic medicine : a journal of the British Diabetic Association · 2022Article
- Maternal Pre-conception Body Mass Index and Fasting Plasma Glucose With the Risk of Pre-term Birth: A Cohort Study Including 4.9 Million Chinese Women.Frontiers in reproductive health · 2021Article
- Glucose Homeostasis, Fetal Growth and Gestational Diabetes Mellitus in Pregnancy after Bariatric Surgery: A Scoping Review.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGestational diabetes mellitus (GDM) is a common metabolic derangement in pregnant women. In the women identified to be at high risk of GDM, a 75 g oral glucose tolerance test (OGTT) at 24-28 wk gestation is the recommended screening test in the United Kingdom as per National Institute for Health and Care Excellence (NICE). Hypoglycaemia following the glucose load is often encountered and the implication of this finding for the pregnancy, fetus and clinical care is unclear.
aimTo determine the prevalence of hypoglycaemia at any time during the screening OGTT and explore its association with birth weight.
methodsAll deliveries between 2009 and 2013 at the local maternity unit of the University hospital were reviewed. Of the total number of 24,154 women without pre-existing diabetes, those who had an OGTT for GDM screening based on NICE recommended risk stratification, who had a singleton delivery and had complete clinical and demographic data for analysis, were included for this study (
resultsAmongst the study cohort (3537 deliveries), 96 (2.7%) women had babies with LBW (< 2500 g). Women who delivered a LBW baby had significantly lower FPG (4.3 ± 0.6 mmol/L,
conclusionA low FPG and 2-h PG ≤ 3.5 mmol/L on 75-gram OGTT are significantly associated with low birth weight in women identified as high risk for GDM. Women of ethnic backgrounds (Asians) appear to be more susceptible to this increased risk and may serve as a separate cohort in whom we should offer more intensive follow up and screening for complications. Cost implications and resources for follow up would need to be looked at in further detail to support these findings.
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