Evidence map›Paper›PMID 31139224›Full record

ArticleJournal of contemporary brachytherapy2019

First report on extended distance between tumor lesion and adjacent organs at risk using interventionally applied balloon catheters: a simple procedure to optimize clinical target volume covering effective isodose in interstitial high-dose-rate brachytherapy of liver malignomas.

Peter Hass, Ingo G Steffen, Maciej Powerski, Konrad Mohnike, Max Seidensticker, Frank Meyer, Thomas Brunner, Robert Damm, Christoph Willich, Mathias Walke and 3 more

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peter HassDepartment of Radiation Oncology, University Hospital, Magdeburg, Germany.
Ingo G SteffenDepartment of Nuclear Medicine, University Medical Center Charité, Berlin, Germany.
Maciej PowerskiInternational School of Image-Guided Interventions, Magdeburg, Germany.
Konrad MohnikeInternational School of Image-Guided Interventions, Magdeburg, Germany.
Max SeidenstickerInternational School of Image-Guided Interventions, Magdeburg, Germany.
Frank MeyerDepartment of General, Abdominal, Vascular, and Transplant Surgery, University Hospital, Magdeburg, Germany.
Thomas BrunnerDepartment of Radiation Oncology, University Hospital, Magdeburg, Germany.
Robert DammDepartment of Radiology and Nuclear Medicine, University Hospital, Magdeburg, Germany.
Christoph WillichDepartment of Radiation Oncology, University Hospital, Magdeburg, Germany.
Mathias WalkeDepartment of Radiation Oncology, University Hospital, Magdeburg, Germany.
Efstratios KaragiannisDepartment of Radiation Oncology, German Oncology Center, Limassol, Cyprus.
Jazan OmariDepartment of Radiology and Nuclear Medicine, University Hospital, Magdeburg, Germany.
Jens RickeInternational School of Image-Guided Interventions, Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOrgans at risk (OARs), which are very close to a clinical target volume (CTV), can compromise effective tumor irradiation. The present study investigated the feasibility and safety of a novel approach, in particular, the extent of the dosimetric effect of distancing CTV from adjacent OARs by means of interventionally applied balloon catheters. MATERIAL AND

methodsPatients with peripheral hepatic malignancies, in whom the critical proximity of an OAR to the CTV in the assessment by contrast-enhanced magnetic resonance imaging (MRI) scans and the preplanning process were included. Additionally, patients underwent placement of an interventional balloon catheter during computed tomography (CT)-guided application of interstitial brachytherapy (iBT) catheters inserted into the tissue between hepatic capsule and adjacent OAR. The virtual position of an OAR without balloon catheter was anticipated and contoured in addition to contouring of CTV and OAR. The calculated dose values for CTV as well as 1 cc of the relevant OAR (D

resultsIn 31 cases, at least one balloon catheter was administered. The mean D

conclusionsThe distancing of the adjacent OARs allows a higher D

Indexed as

balloon cathetersclinical target volume (CTV)dose per 1 cc (D1cc)dose volume histogram (DVH)interstitial high-dose-rate (HDR) brachytherapy (iBT)liver malignanciesorgan at risk (OAR)

Identifiers

PMID31139224
PMCPMC6536139

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.