Evidence map›Paper›PMID 31139188›Full record

ArticleFrontiers in immunology2019

DNA Vaccines Against Mycoplasma Elicit Humoral Immune Responses in Ostriches.

Martha Wium, Hester Isabella Jonker, Adriaan Jacobus Olivier, Dirk Uwe Bellstedt, Annelise Botes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Martha WiumDepartment of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.
Hester Isabella JonkerDepartment of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.
Adriaan Jacobus OlivierKlein Karoo International, Oudtshoorn, South Africa.
Dirk Uwe BellstedtDepartment of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.
Annelise BotesDepartment of Biochemistry, Stellenbosch University, Stellenbosch, South Africa.
Stellenbosch University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In ostriches, the population densities resulting from intensive rearing increases susceptibility to pathogens such as mycoplasmas. In addition to good management practices, vaccination offers an attractive alternative for controlling mycoplasma infections in food animals, instead of using antibiotics, which often leave unacceptable residues. The use of live attenuated vaccines, however, carry the concern of reversion to virulence or genetic recombination with field strains. Currently there are no commercially available vaccines against ostrich-infecting mycoplasmas and this study therefore set out to develop and evaluate the use of a DNA vaccine against mycoplasma infections in ostriches using an OppA protein as antigen. To this end, the

Indexed as

AnimalsAntibodies, BacterialBacterial ProteinsBacterial VaccinesImmunity, HumoralLipoproteinsMycoplasmaStruthioniformesVaccinationVaccines, AttenuatedVaccines, DNAVaccines, SyntheticAntibodies, BacterialBacterial ProteinsBacterial VaccinesLipoproteinsoligopeptide-binding protein, bacteriaVaccines, AttenuatedVaccines, DNAVaccines, Syntheticantibody responseDNA vaccinemycoplasmaOppAostrich

Identifiers

PMID31139188
PMCPMC6527592
OpenAlexW2946196986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.