Evidence map›Paper›PMID 31139182›Full record

Trial reportFrontiers in immunology2019

Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness.

Emily R Levy, Wai-Ki Yip, Michael Super, Jill M Ferdinands, Anushay J Mistry, Margaret M Newhams, Yu Zhang, Helen C Su, Gwenn E McLaughlin, Anil Sapru and 9 more

Open access · goldAbstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Pathobiology, Severity, and Risk Stratification of Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 1 country.

Emily R LevyDivision of Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, United States.
Wai-Ki YipFoundation Medicine Inc., Cambridge, MA, United States.
Michael SuperWyss Institute at Harvard University, Boston, MA, United States.
Jill M FerdinandsInfluenza Division, US Centers for Disease Control and Prevention, Atlanta, GA, United States.
Anushay J MistryDivision of Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, United States.
Margaret M NewhamsDivision of Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, United States.
Yu ZhangLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Helen C SuLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Gwenn E McLaughlinDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL, United States.
Anil SapruCritical Care Medicine Division, Department of Pediatrics, Children's Hospital of Los Angeles, University of California, Los Angeles, Los Angeles, CA, United States.
Laura L LoftisSection of Critical Care Medicine, Department of Pediatrics, Texas Children's Hospital, Houston, TX, United States.
Scott L WeissDepartment of Anesthesiology and Critical Care, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
Mark W HallDivision of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH, United States.
Natalie CvijanovichDepartment of Pediatrics, Benioff Children's Hospital Oakland, University California San Francisco, Oakland, CA, United States.
Adam SchwarzDepartment of Pediatrics, Children's Hospital of Orange County, Orange, CA, United States.
Keiko M TarquinioDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Children's Healthcare of Atlanta at Egleston, Emory University School of Medicine, Atlanta, GA, United States.
Peter M MouraniSection of Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, United States.
PALISI PICFLU Investigators
Adrienne G RandolphDivision of Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital and Department of Anaesthesia, Harvard Medical School, Boston, MA, United States.
Boston Children's Hospital · USNational Institutes of Health · USCenters for Disease Control and Prevention · USChildren's Hospital Colorado · USChildren's Hospital of Los Angeles · USChildren's Hospital of Orange County · USChildren's Hospital of Philadelphia · USEmory University · USFoundation Medicine (United States)Harvard University · USNationwide Children's Hospital · USOakland University · USTexas Children's Hospital · USUniversity of Miami · US

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI JENNIFER W MACK · 1985 to 2026
$330.6M
Defining New Human Immunodeficiency and Immunodysregulation DisordersZIAAI001059 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SU, HELEN CHUN-HUI · 2009 to 2025
$20.5M
Genetic Epidemiology of Life-Threatening Influenza in ChildrenR01AI084011 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI RANDOLPH, ADRIENNE G · 2010 to 2013
$3.1M
Genetic Epidemiology of Life-Threatening Influenza Infection in ChildrenR56AI084011 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI RANDOLPH, ADRIENNE G · 2009 to 2009
$712k
Genes Associated with MODS in Children with Severe Acute Respiratory InfectionsR21HD095228 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI RANDOLPH, ADRIENNE G · 2018 to 2019
$445k
NCI NIH HHS P30 CA006516NIAID NIH HHS R01 AI084011NIAID NIH HHS R56 AI084011NICHD NIH HHS R21 HD095228
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CoinfectionGenetic Predisposition to DiseaseInfluenza A virusInfluenza, HumanMannose-Binding LectinMethicillin-Resistant Staphylococcus aureusMutation, MissenseStaphylococcal InfectionsAdolescentAmino Acid SubstitutionChildChild, PreschoolCritical IllnessFemaleHumansInfantMannose-Binding LectinMBL2 protein, humancritical illnessinfluenzaMBLmethicillin-resistant Staphylococcus aureusmortalitypediatricsepsis

Identifiers

PMID31139182
PMCPMC6518443
OpenAlexW2944775064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.