Evidence map›Paper›PMID 31138822›Full record

ArticleScientific reports2019

Breast-lesions characterization using Quantitative Ultrasound features of peritumoral tissue.

Ziemowit Klimonda, Piotr Karwat, Katarzyna Dobruch-Sobczak, Hanna Piotrzkowska-Wróblewska, Jerzy Litniewski

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematized Review of Quantitative Ultrasound Based on First-Order Speckle Statistics.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024
    Pooled it
  2. Review
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  5. Influences of Variability in Attenuation Compensation on the Estimation of Backscatter Coefficient of Median Nerves in Vivo.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
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  14. Breast Tumor Classification Using Intratumoral Quantitative Ultrasound Descriptors.Computational and mathematical methods in medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ziemowit KlimondaInstitute of Fundamental Technological Research, Department of Ultrasound, Pawińskiego 5b, 02-106, Warsaw, Poland. zklim@ippt.pan.pl.ORCID http://orcid.org/0000-0003-1695-7096
Piotr KarwatInstitute of Fundamental Technological Research, Department of Ultrasound, Pawińskiego 5b, 02-106, Warsaw, Poland.
Katarzyna Dobruch-SobczakInstitute of Fundamental Technological Research, Department of Ultrasound, Pawińskiego 5b, 02-106, Warsaw, Poland.
Hanna Piotrzkowska-WróblewskaInstitute of Fundamental Technological Research, Department of Ultrasound, Pawińskiego 5b, 02-106, Warsaw, Poland.
Jerzy LitniewskiInstitute of Fundamental Technological Research, Department of Ultrasound, Pawińskiego 5b, 02-106, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presented studies evaluate for the first time the efficiency of tumour classification based on the quantitative analysis of ultrasound data originating from the tissue surrounding the tumour. 116 patients took part in the study after qualifying for biopsy due to suspicious breast changes. The RF signals collected from the tumour and tumour-surroundings were processed to determine quantitative measures consisting of Nakagami distribution shape parameter, entropy, and texture parameters. The utility of parameters for the classification of benign and malignant lesions was assessed in relation to the results of histopathology. The best multi-parametric classifier reached an AUC of 0.92 and of 0.83 for outer and intra-tumour data, respectively. A classifier composed of two types of parameters, parameters based on signals scattered in the tumour and in the surrounding tissue, allowed the classification of breast changes with sensitivity of 93%, specificity of 88%, and AUC of 0.94. Among the 4095 multi-parameter classifiers tested, only in eight cases the result of classification based on data from the surrounding tumour tissue was worse than when using tumour data. The presented results indicate the high usefulness of QUS analysis of echoes from the tissue surrounding the tumour in the classification of breast lesions.

Indexed as

Tumor MicroenvironmentArea Under CurveBiopsy, Fine-NeedleBreastBreast NeoplasmsEntropyFemaleHumansPrognosisSensitivity and SpecificityTerminology as TopicUltrasonography, Mammary

Identifiers

PMID31138822
PMCPMC6538710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.