ArticleScientific reports2019
A rapid beam simulation framework for transcranial focused ultrasound.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 69 citations in OpenAlex.
- From Skull Density Ratio-based eligibility to efficiency-informed planning: Predictive modeling of thermal response in MR-guided focused ultrasound.Medical physics · 2026Article
- Performance of a through-transmit aberration correction method for transcranial focused ultrasound: Simulation and experimental evaluation.The Journal of the Acoustical Society of America · 2026Article
- Empirical limitations of current low-intensity focused ultrasound simulation platforms.medRxiv : the preprint server for health sciences · 2026Article
- A deep-learning model for one-shot transcranial ultrasound simulation and phase aberration correction.Medical physics · 2026Article
- Article
- The speed of sound in skull-mimicking digital phantoms depends on the microstructure.Physics in medicine and biology · 2025Article
- Influence of bone microstructure on ultrasound loss through skull-mimicking digital phantoms.Medical physics · 2025Article
- Imaging the brain by traversing the skull with light and sound.Nature biomedical engineering · 2025Review
- A comparative study of experimental and simulated ultrasound beam propagation through cranial bones.Physics in medicine and biology · 2025Article
- A Physiological Marker for Deep Brain Ultrasonic Neuromodulation.Neuromodulation : journal of the International Neuromodulation Society · 2025Article
- Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology.Neuron · 2024Article
- Robust deep learning estimation of cortical bone porosity from MR T1-weighted images for individualized transcranial focused ultrasound planning.medRxiv : the preprint server for health sciences · 2024Article
- Device for Multifocal Delivery of Ultrasound Into Deep Brain Regions in Humans.IEEE transactions on bio-medical engineering · 2024Article
- Evaluation of acoustic-thermal simulations of in vivo magnetic resonance guided focused ultrasound ablative therapy.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024Article
- Improving Sonication Efficiency in Transcranial MR-Guided Focused Ultrasound Treatment: A Patient-Data Simulation Study.Bioengineering (Basel, Switzerland) · 2023Article
- The influence of bone model geometries on the determination of skull acoustic properties.International journal for numerical methods in biomedical engineering · 2023Article
- Influence of cerebrospinal fluid on power absorption during transcranial magnetic resonance-guided focused ultrasound treatment.Medical physics · 2023Article
- Generating Patient-Specific Acoustic Simulations for Transcranial Focused Ultrasound Procedures Based on Optical Tracking Information.IEEE open journal of ultrasonics, ferroelectrics, and frequency control · 2023Article
- Numerical and experimental evaluation of low-intensity transcranial focused ultrasound wave propagation using human skulls for brain neuromodulation.Medical physics · 2023Article
- Transcranial ultrasound neuromodulation of the thalamic visual pathway in a large animal model and the dose-response relationship with MR-ARFI.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Transcranial focused ultrasound is a non-invasive therapeutic modality that can be used to treat essential tremor. Beams of energy are focused into a small spot in the thalamus, resulting in tissue heating and ablation. Here, we report on a rapid 3D numeric simulation framework that can be used to predict focal spot characteristics prior to the application of ultrasound. By comparing with magnetic resonance proton resonance frequency shift thermometry (MR thermometry) data acquired during treatments of essential tremor, we verified that our simulation framework can be used to predict focal spot position, and with patient-specific calibration, predict focal spot temperature rise. Preliminary data suggests that lateral smearing of the focal spot can be simulated. The framework may also be relevant for other therapeutic ultrasound applications such as blood brain barrier opening and neuromodulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.