Evidence map›Paper›PMID 31138781›Full record

ArticleCell death & disease2019

Translational downregulation of Twist1 expression by antiproliferative gene, B-cell translocation gene 2, in the triple negative breast cancer cells.

Preethi Devanand, Santhoshkumar Sundaramoorthy, Min Sook Ryu, Aravinth Kumar Jayabalan, Takbum Ohn, In Kyoung Lim

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. TWIST1 upregulation affects E-cadherin expression in brain metastases.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Preethi DevanandDepartment of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
Santhoshkumar SundaramoorthyDepartment of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
Min Sook RyuDepartment of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Republic of Korea.
Aravinth Kumar JayabalanDepartment of Cellular and Molecular Medicine, College of Medicine, Chosun University, Gwangju, 61452, Republic of Korea.
Takbum OhnDepartment of Cellular and Molecular Medicine, College of Medicine, Chosun University, Gwangju, 61452, Republic of Korea.
In Kyoung LimDepartment of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon, 16499, Republic of Korea. iklim@ajou.ac.kr.
Ajou University · KRChosun University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twist1, a key transcription factor regulating epithelial-mesenchymal transition and cancer metastasis, is highly expressed in invasive cancers in contrast to the loss of BTG2

Indexed as

Adaptor Proteins, Signal TransducingAnimalsCell Cycle ProteinsDown-RegulationEukaryotic Initiation Factor-2FemaleGene Expression Regulation, NeoplasticHEK293 CellsHeLa CellsHumansImmediate-Early ProteinsLysosomesMCF-7 CellsMiceMice, Inbred C57BLMice, KnockoutAdaptor Proteins, Signal TransducingBTG2 protein, humanCell Cycle ProteinsEIF4EBP1 protein, humanEukaryotic Initiation Factor-2Immediate-Early ProteinsNuclear ProteinsPeptide Elongation FactorsProteasome Endopeptidase ComplexTumor Suppressor ProteinsTWIST1 protein, humanTwist-Related Protein 1

Identifiers

PMID31138781
PMCPMC6538657
OpenAlexW2947423853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.