Evidence map›Paper›PMID 31138745›Full record

ArticlemBio2019

Live Monitoring and Analysis of Fungal Growth, Viability, and Mycelial Morphology Using the IncuCyte NeuroTrack Processing Module.

Sebastian Wurster, Pappanaicken R Kumaresan, Nathaniel D Albert, Paul J Hauser, Russell E Lewis, Dimitrios P Kontoyiannis

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Sebastian Wurster *Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA stwurster@mdanderson.org dkontoyi@mdanderson.org.ORCID 0000-0002-7784-7256
Pappanaicken R Kumaresan *Department of Pediatrics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Nathaniel D AlbertDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Paul J HauserDepartment of Pediatrics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Russell E LewisClinic of Infectious Diseases, S'Orsola-Malpighi Hospital, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Dimitrios P KontoyiannisDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA stwurster@mdanderson.org dkontoyi@mdanderson.org.ORCID 0000-0002-8051-2940
The University of Texas MD Anderson Cancer Center · USIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · IT

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Redirected T Cell Therapy to Cure Invasive Fungal InfectionsR33AI127381 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONTOYIANNIS, DIMITRIOS P, KUMAR, PAPPANAICKEN RANGASAMY · 2019 to 2021
$1.4M
Redirected T Cell Therapy to Cure Invasive Fungal InfectionsR21AI127381 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONTOYIANNIS, DIMITRIOS P, KUMAR, PAPPANAICKEN RANGASAMY · 2017 to 2018
$436k
NCI NIH HHS P30 CA016672NIAID NIH HHS R21 AI127381NIAID NIH HHS R33 AI127381
6 · The paper itself

Abstract

Efficient live-imaging methods are pivotal to understand fungal morphogenesis, especially as it relates to interactions with host immune cells and mechanisms of antifungal drugs. Due to the notable similarities in growth patterns of neuronal cells and mycelial networks, we sought to repurpose the NeuroTrack (NT) processing module of the IncuCyte time-lapse microscopy system as a tool to quantify mycelial growth and branching of pathogenic fungi. We showed the robustness of NT analysis to study

Indexed as

Microbial ViabilityTime-Lapse ImagingAspergillus fumigatusCandida albicansFungiMicrobial Sensitivity TestsMyceliumReproducibility of Resultsantifungal treatmentfungal pathogenslive imagingmorphogenesismycelium

Identifiers

PMID31138745
PMCPMC6538782
OpenAlexW2946182012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.