ArticlemSystems2019
Reconciling Ecological and Engineering Design Principles for Building Microbiomes.
Article in mSystems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed.
- Engineering the plant microbiome: synthetic community approaches to enhance crop protection.Frontiers in plant science · 2025Review
- Rationally designed microbial communities in agri-food production systems: from research to market.ISME communications · 2025Article
- Insights into the biotic factors driving the outcome of coalescence events between soil bacterial communities.ISME communications · 2025Article
- Concepts and criteria defining emerging microbiome applications.Microbial biotechnology · 2024Article
- The hydrocarbon pollution crisis: Harnessing the earth hydrocarbon-degrading microbiome.Microbial biotechnology · 2024Article
- Engineering natural microbiomes toward enhanced bioremediation by microbiome modeling.Nature communications · 2024Article
- Article
- Repeated introduction of micropollutants enhances microbial succession despite stable degradation patterns.ISME communications · 2022Article
- Guided by Microbes: Applying Community Coalescence Principles for Predictive Microbiome Engineering.mSystems · 2021Article
- Horizontal 'gene drives' harness indigenous bacteria for bioremediation.Scientific reports · 2020Article
- Function-Driven Design of Lactic Acid Bacteria Co-cultures to Produce New Fermented Food Associating Milk and Lupin.Frontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Simplified microbial communities, or "benchtop microbiomes," enable us to manage the profound complexity of microbial ecosystems. Widespread activities aiming to design and control communities result in novel resources for testing ecological theories and also for realizing new biotechnologies. There is much to be gained by reconciling engineering design principles with ecological processes that shape microbiomes in nature. In this short Perspective, I will address how natural processes such as environmental filtering, the establishment of priority effects, and community "blending" (coalescence) can be harnessed for engineering microbiomes from complex starting materials. I will also discuss how future microbiome architects may draw inspiration from modern practices in synthetic biology. This topic is based on an important overarching research goal, which is to understand how natural forces shape microbial communities and interspecies interactions such that new engineering design principles can be extracted to promote human health or energy and environmental sustainability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.