Evidence map›Paper›PMID 31138706›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Fate plasticity and reprogramming in genetically distinct populations of

Victor M Lewis, Lauren M Saunders, Tracy A Larson, Emily J Bain, Samantha L Sturiale, Dvir Gur, Sarwat Chowdhury, Jessica D Flynn, Michael C Allen, Dimitri D Deheyn and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 80 citations in OpenAlex.

  1. Integrated Transcriptomic Analysis of Skin Pigmentation Development inInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Lysosome-related organelles orchestrate guanine crystal formation in pigment cells.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Cell type diversification and phenotype convergence underlying white fin-ornamentation of cyprinid fishes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Tyrosinase-Deficient Skin Melanophore Lineage inInternational journal of molecular sciences · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Specialized molecular pathways drive the formation of light-scattering assemblies in leucophores.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Agouti and BMP signaling drive a naturally occurring fate conversion of melanophores to leucophores in zebrafish.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Article
  19. Experimentally Manipulating the Thyroid Hormone Axis in Zebrafish.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Victor M LewisDepartment of Biology, University of Virginia, Charlottesville, VA 22903.
Lauren M SaundersDepartment of Biology, University of Virginia, Charlottesville, VA 22903.
Tracy A LarsonDepartment of Biology, University of Virginia, Charlottesville, VA 22903.
Emily J BainDepartment of Biology, University of Virginia, Charlottesville, VA 22903.
Samantha L SturialeDepartment of Biology, University of Virginia, Charlottesville, VA 22903.
Dvir GurJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147.
Sarwat ChowdhuryClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Jessica D FlynnNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.
Michael C AllenMarine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Dimitri D DeheynMarine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA 92093.
Jennifer C LeeNational Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-0506-8349
Julian A SimonClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Jennifer Lippincott-SchwartzJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147.
David W RaibleDepartment of Biology, University of Washington, Seattle, WA 98195.
David M ParichyDepartment of Biology, University of Virginia, Charlottesville, VA 22903; dparichy@virginia.edu.ORCID 0000-0003-2771-6095
University of Virginia · USNational Institutes of Health · USUniversity of Washington · USFred Hutch Cancer Center · USScripps Institution of Oceanography · USHoward Hughes Medical Institute · US

Funding

Vision Research CoreP30EY001730 · NEI · UNIVERSITY OF WASHINGTON · PI MAUREEN E NEITZ · 1985 to 2026
$23.5M
TRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0M
Fish facility enhancementR35GM122471 · NIGMS · UNIVERSITY OF WASHINGTON · PI DAVID M PARICHY · 2017 to 2026
$6.4M
Raman Spectroscopic Studies of AmyloidsZIAHL006236 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEE, JENNIFER · 2018 to 2025
$5.5M
NEI NIH HHS P30 EY001730NIGMS NIH HHS R35 GM122471NIGMS NIH HHS T32 GM007270
6 · The paper itself

Abstract

Understanding genetic and cellular bases of adult form remains a fundamental goal at the intersection of developmental and evolutionary biology. The skin pigment cells of vertebrates, derived from embryonic neural crest, are a useful system for elucidating mechanisms of fate specification, pattern formation, and how particular phenotypes impact organismal behavior and ecology. In a survey of

Indexed as

AnimalsCell PlasticityEmbryo, NonmammalianGene Expression Regulation, DevelopmentalGenetics, PopulationMelanophoresMutationNeural CrestPhenotypePigmentationTranscriptomeZebrafishevolutionneural crestpigmentationtransdifferentiationzebrafish

Identifiers

PMID31138706
PMCPMC6575160
OpenAlexW2951370628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.