Evidence map›Paper›PMID 31138695›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Adverse organogenesis and predisposed long-term metabolic syndrome from prenatal exposure to fine particulate matter.

Guoyao Wu, Jacob Brown, Misti L Zamora, Alyssa Miller, M Carey Satterfield, Cynthia J Meininger, Chelsie B Steinhauser, Gregory A Johnson, Robert C Burghardt, Fuller W Bazer and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Prenatal Exposure to PMEnvironment & health (Washington, D.C.) · 2025
    Article
  4. Article
  5. NNanotoxicology · 2023
    Article
  6. Article
  7. Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs.Experimental biology and medicine (Maywood, N.J.) · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Toxicological Effects of Secondary Air Pollutants.Chemical research in Chinese universities · 2023
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Guoyao WuDepartment of Animal Science, Texas A&M University, College Station, TX 77843; g-wu@tamu.edu mjmolina@ucsd.edu renyi-zhang@geos.tamu.edu.
Jacob BrownDepartment of Animal Science, Texas A&M University, College Station, TX 77843.
Misti L ZamoraDepartment of Atmospheric Science, Texas A&M University, College Station, TX 77843.
Alyssa MillerDepartment of Animal Science, Texas A&M University, College Station, TX 77843.
M Carey SatterfieldDepartment of Animal Science, Texas A&M University, College Station, TX 77843.
Cynthia J MeiningerDepartment of Medical Physiology, Texas A&M University, College Station, TX 77843.
Chelsie B SteinhauserDepartment of Integrative Veterinary Bioscience, Texas A&M University, College Station, TX 77843.
Gregory A JohnsonDepartment of Integrative Veterinary Bioscience, Texas A&M University, College Station, TX 77843.
Robert C BurghardtDepartment of Integrative Veterinary Bioscience, Texas A&M University, College Station, TX 77843.
Fuller W BazerDepartment of Animal Science, Texas A&M University, College Station, TX 77843.ORCID 0000-0002-5823-5086
Yixin LiDepartment of Chemistry, Texas A&M University, College Station, TX 77843.
Natalie M JohnsonDepartment of Environmental & Occupational Health, Texas A&M University, College Station, TX 77843.
Mario J MolinaDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093 g-wu@tamu.edu mjmolina@ucsd.edu renyi-zhang@geos.tamu.edu.
Renyi ZhangDepartment of Atmospheric Science, Texas A&M University, College Station, TX 77843; g-wu@tamu.edu mjmolina@ucsd.edu renyi-zhang@geos.tamu.edu.
Texas A&M University · USUniversity of California San Diego · US

Funding

Mechanisms of particulate matter driven infant respiratory diseaseR01ES028866 · NIEHS · TEXAS A&M UNIVERSITY · PI JOHNSON, NATALIE M · 2018 to 2022
$2.1M
NIEHS NIH HHS R01 ES028866
6 · The paper itself

Abstract

Exposure to fine particulate matter (PM) during pregnancy is associated with high risks of birth defects/fatality and adverse long-term postnatal health. However, limited mechanistic data are available to assess the detailed impacts of prenatal PM exposure. Here we evaluate fine PM exposure during pregnancy on prenatal/postnatal organogenesis in offspring and in predisposing metabolic syndrome for adult life. Between days 0 and 18 of gestation, two groups of adult female rats (

Indexed as

Air PollutionAnimalsBirth WeightDisease SusceptibilityEnvironmental ExposureFatty AcidsFemaleGlucoseMaleMaternal ExposureMetabolic SyndromeOrganogenesisParticulate MatterPregnancyPrenatal Exposure Delayed EffectsRatsFatty AcidsGlucoseParticulate Matterair pollutionmetabolismpostnatal healthpregnancy outcomes

Identifiers

PMID31138695
PMCPMC6575589
OpenAlexW2946857605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.