Evidence map›Paper›PMID 31138663›Full record

ArticleMolecular and cellular biology2019

Aren E Marshall, Michael V Roes, Daniel T Passos, Megan C DeWeerd, Andrea C Chaikovsky, Julien Sage, Christopher J Howlett, Frederick A Dick

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

  1. Science translational medicine · 2023
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  15. TargetingCancers · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Aren E MarshallLondon Regional Cancer Program, Lawson Health Research Institute, London, Ontario, Canada.
Michael V RoesLondon Regional Cancer Program, Lawson Health Research Institute, London, Ontario, Canada.
Daniel T PassosLondon Regional Cancer Program, Lawson Health Research Institute, London, Ontario, Canada.ORCID 0000-0002-3530-2821
Megan C DeWeerdLondon Regional Cancer Program, Lawson Health Research Institute, London, Ontario, Canada.
Andrea C ChaikovskyDepartment of Pediatrics, Stanford University, Stanford, California, USA.
Julien SageDepartment of Pediatrics, Stanford University, Stanford, California, USA.
Christopher J HowlettDepartment of Pathology and Laboratory Medicine, Western University, London, Ontario, Canada.
Frederick A DickLondon Regional Cancer Program, Lawson Health Research Institute, London, Ontario, Canada fdick@uwo.ca.
Western University · CAStanford University · US

Funding

Leveraging innovative technologies in basic and clinical cancer researchT32CA009302 · NCI · STANFORD UNIVERSITY · PI LAURA D ATTARDI, Aaron M Newman · 1985 to 2026
$19.1M
Molecular basis of tumor suppression by Cdk4/6 inhibitionR01CA228413 · NCI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI RUBIN, SETH MICHAEL, SAGE, JULIEN · 2019 to 2023
$1.8M
CIHR MOP 324579NCI NIH HHS R01 CA228413NCI NIH HHS T32 CA009302
6 · The paper itself

Abstract

Proliferative control in cancer cells is frequently disrupted by mutations in the retinoblastoma protein (RB) pathway. Intriguingly,

Indexed as

DNA DamageSequence DeletionAnimalsCell Line, TumorCell ProliferationCRISPR-Cas SystemsDisease ProgressionHumansLung NeoplasmsMiceNeoplasm TransplantationReactive Oxygen SpeciesRetinoblastoma Binding ProteinsUbiquitin-Protein LigasesRB1 protein, humanReactive Oxygen SpeciesRetinoblastoma Binding ProteinsUbiquitin-Protein Ligasescell cyclechemotherapyhaploinsufficiencymetastasismitosis

Identifiers

PMID31138663
PMCPMC6664603
OpenAlexW2950587411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.