ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019
The Risk of Hospitalization for Motor Vehicle Accident Injury in Narcolepsy and the Benefits of Stimulant Use: A Nationwide Cohort Study in Taiwan.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- Effects of solriamfetol on on-the-road driving in participants with narcolepsy: A randomised crossover trial.Human psychopharmacology · 2023Trial
- Mortality in narcolepsy and other sleep clinic patients: a 25-year propensity-matched VA cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Zolpidem use and the risk of arrhythmia: A nationwide population-based cohort study in Taiwan.Journal of the Chinese Medical Association : JCMA · 2026Article
- Causality of blood metabolites and narcolepsy type 1: A Mendelian randomization study.Medicine · 2025Article
- Healthcare Burden and Productivity Loss Due to Narcolepsy in Sweden.Clocks & sleep · 2025Article
- Case Report: Narcolepsy patients masked behind obstructive sleep apnea syndrome (OSAS): report of 2 cases and literature review.Frontiers in neuroscience · 2025Article
- Narcolepsy and risk of traumatic injury: a population-based matched cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Associations between T-cell traits and narcolepsy type 1: new insights from a Mendelian randomization study.Frontiers in neurology · 2024Article
- The Usage of Histamine Type 1 Receptor Antagonist and Risk of Dementia in the Elderly: A Nationwide Cohort Study.Frontiers in aging neuroscience · 2022Article
- Long-term atomoxetine-oxybutynin combination use may be beneficial for the prevention of obstructive sleep apnea.Scientific reports · 2021Article
- The Association Between Asthma and Narcolepsy: A Nationwide Case-Control Study in Taiwan.Nature and science of sleep · 2021Article
- Therapeutic Strategies for Mitigating Driving Risk in Patients with Narcolepsy.Therapeutics and clinical risk management · 2020Review
- Lisdexamfetamine to improve excessive daytime sleepiness and weight management in narcolepsy: a case series.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo examine the risk of hospitalization for motor vehicle accident injury (MVAI) in patients with narcolepsy and the effects of stimulant use on MVAI occurrence in patients with narcolepsy.
methodsThis is a population-based, retrospective cohort study using Taiwan's National Health Insurance Research Database between 2000 and 2013. We included patients with narcolepsy based on the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes, 347. The case and matched control participants were selected in a ratio of 1:3, and the traffic accident (ICD-9-CM codes: E810-E819) plus injury codes (ICD-9-CM codes: 800.xx-999.xx) due to MVAI following hospitalization were used for the study outcome. The type of injury, causes, intentionality, and the effects of stimulant use on patients with narcolepsy were also assessed.
resultsA total of 1,316 participants were enrolled, including 329 participants with narcolepsy and 987 participants without narcolepsy. During a 14-year follow-up period, a total of 104 participants had MVAI, of whom 47 (1,559.54 per 100,000 person-years) belonged to the narcolepsy cohort and 57 (556.21 per 100,000 person-years) to the non-narcolepsy cohort. After adjusting for covariates, the risk of hospitalization for MVAI among participants with narcolepsy was still significantly higher than those without narcolepsy (adjusted hazard ratio = 6.725; 95% confidence interval = 4.421-10.231;
conclusionsPatients with narcolepsy may have a higher risk of hospitalization for MVAI and stimulant use could mitigate such risk.
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Registered trials
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