Evidence map›Paper›PMID 31138379›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

Adherence to Positive Airway Pressure for the Treatment of Obstructive Sleep Apnea in Children With Developmental Disabilities.

Eun Kyeong Kang, Melissa S Xanthopoulos, Ji Young Kim, Casandra Arevalo, Justine Shults, Suzanne E Beck, Carole L Marcus, Ignacio E Tapia

Registry-linked trialOpen access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04124471 (Positive Airway Pressure for the Treatment of the Obstructive Sleep Apnea Syndrome in Children With Down Syndrome), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04124471 nacompletednot on this map

Positive Airway Pressure for the Treatment of the Obstructive Sleep Apnea Syndrome in Children With Down Syndrome (Stage 1)

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2019 to 2022Enrolled42ConditionsDown Syndrome, Obstructive Sleep ApneaArmsOpen-ended semi-structured interviews
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Adherence to positive airway pressure therapy in patients with Down syndrome: assessing cloud-based monitoring data.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  5. How adherent are children with Down syndrome and obstructive sleep apnea to positive airway pressure therapy?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  6. Preliminary investigation of obstructive sleep apnea and Alzheimer's disease in down syndrome.Sleep advances : a journal of the Sleep Research Society · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Clinical utility of repeated positive airway pressure titrations in children with obstructive sleep apnea syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  12. Article
  13. Article
  14. Sleep Disorders in Adults with Down Syndrome.Journal of clinical medicine · 2021
    Review
  15. Defining the patterns of PAP adherence in pediatric obstructive sleep apnea: a clustering analysis using real-world data.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  16. Article
  17. Factors related to positive airway pressure therapy adherence in children with obesity and sleep-disordered breathing.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Eun Kyeong KangSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Melissa S XanthopoulosSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Ji Young KimSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Casandra ArevaloSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Justine ShultsSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Suzanne E BeckSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Carole L MarcusSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Ignacio E TapiaSleep Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Children's Hospital of Philadelphia · US

Funding

INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR024134 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2006 to 2011
$70.4M
Cerebral blood flow and neurocognition in children with obstructive sleep apneaK01HL130719 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI TAPIA, IGNACIO ESTEBAN · 2016 to 2020
$813k
NCRR NIH HHS UL1 RR024134NHLBI NIH HHS K01 HL130719
6 · The paper itself

Abstract

STUDY

objectivesTo determine whether adherence to positive airway pressure (PAP) differs in children with developmental disabilities (DD) compared to typically developing (TD) children.

methodsPAP adherence of 240 children initiated on PAP for obstructive sleep apnea (OSA) was retrospectively analyzed. Adherence between groups, expressed as percentage of nights used and hours of usage on nights used at 3 and 6 months, was compared. Predictive factors of adherence were studied using a median regression model.

resultsA total of 103 children with DD (median [interquartile range] age = 7.9 [3.2-13.1] years) and 137 TD (11.0 [5.5-16.1],

conclusionsChildren with DD had better PAP adherence expressed as percentage of nights used than TD children. Hours of usage on nights used at 3 and 6 months were similar between groups and improved over time. Higher income and titration at or before 6 months were predictive of adherence in all children. These findings indicate that children with DD can successfully wear PAP.

Indexed as

Age FactorsChildChild BehaviorChild DevelopmentContinuous Positive Airway PressureDevelopmental DisabilitiesFemaleFollow-Up StudiesHumansMalePatient CompliancePolysomnographyRetrospective StudiesSleep Apnea, ObstructiveTreatment Outcomeadherencechildrendevelopmental disabilitiesobstructive sleep apneapositive airway pressure

Identifiers

PMID31138379
PMCPMC6557645
OpenAlexW2949439499

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.