Evidence map›Paper›PMID 31138361›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2019

West Nile virus infection in individuals with pre-existing Usutu virus immunity, northern Italy, 2018.

Alessandro Sinigaglia, Monia Pacenti, Thomas Martello, Silvana Pagni, Elisa Franchin, Luisa Barzon

Abstract readCase Reports
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro SinigagliaDepartment of Molecular Medicine, University of Padova, Padova, Italy.
Monia PacentiMicrobiology and Virology Unit, Padova University Hospital, Padova, Italy.
Thomas MartelloDepartment of Molecular Medicine, University of Padova, Padova, Italy.
Silvana PagniDepartment of Molecular Medicine, University of Padova, Padova, Italy.
Elisa FranchinDepartment of Molecular Medicine, University of Padova, Padova, Italy.
Luisa BarzonDepartment of Molecular Medicine, University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2018, there was a large West Nile virus (WNV) outbreak in northern Italy. We observed five atypical cases of WNV infection that were characterised by the presence of WNV RNA and WNV IgG at the time of diagnosis, but no IgM response during follow-up. Neutralisation assays demonstrated pre-existing Usutu virus immunity in all patients. Besides challenging diagnosis, the immunological crosstalk between the two viruses warrants further investigation on possible cross-protection or infection enhancement effects.

Indexed as

Public Health SurveillanceAdultAnimalsAntibodies, NeutralizingAntibodies, ViralCulexDisease OutbreaksEnzyme-Linked Immunosorbent AssayFemaleFlavivirusHumansImmunoglobulin GItalyMaleMiddle AgedNeutralization TestsAntibodies, NeutralizingAntibodies, ViralImmunoglobulin Gantibody cross-reactivitycross-protectionsecondary infectionUsutu virusWest Nile virus

Identifiers

PMID31138361
PMCPMC6540647

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.