SynthesisBMC surgery2019
Laparoscopy versus open appendectomy for elderly patients, a meta-analysis and systematic review.
Synthesis in BMC surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Meta-analysis of the clinical efficacy of laparoscopic appendectomy in the treatment of acute appendicitis.World journal of emergency surgery : WJES · 2022Pooled it
- Comparison of Clinical Features and Outcomes of Appendectomy in Elderly vs. Non-Elderly: A Systematic Review and Meta-Analysis.Frontiers in surgery · 2022Pooled it
- Laparoscopic appendectomy versus antibiotic treatment for acute appendicitis-a systematic review.International journal of colorectal disease · 2021Pooled it
- Acute Appendicitis in Childhood and Adulthood.Deutsches Arzteblatt international · 2020Pooled it
- Influence of sarcopenia and frailty in the management of elderly patients with acute appendicitis.World journal of clinical cases · 2024Article
- Are Preoperative CT Findings Useful in Predicting the Duration of Laparoscopic Appendectomy in Pediatric Patients? A Single Center Study.Journal of clinical medicine · 2024Article
- Postoperative Complications Following Appendectomy: A Single-Center Retrospective Study.Cureus · 2024Article
- Restoration of Pulmonary Compliance after Laparoscopic Gynecologic Surgery Using a Recruitment Maneuver.Journal of personalized medicine · 2024Article
- Cesena guidelines: WSES consensus statement on laparoscopic-first approach to general surgery emergencies and abdominal trauma.World journal of emergency surgery : WJES · 2023Article
- Surgical and oncologic outcomes in surgically treated women 80 years and older with endometrioid endometrial cancer as a function of their comorbidities.Gynecologic oncology reports · 2023Article
- Application and curative effect of laparoscopic purse-string sutures in the treatment of adult acute complicated appendicitis.BMC surgery · 2023Article
- Acute appendicitis over the age of 50: The evaluation of the impact of clinical variables on operative and post-operative outcomes.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Clinical-pathological features and treatment of acute appendicitis in the very elderly: an interim analysis of the FRAILESEL Italian multicentre prospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Determination of factors associated with perforation in patients with geriatric acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Acute appendicitis-advances and controversies.World journal of gastrointestinal surgery · 2021Review
- Acute Appendicitis in the Elderly: A Literature Review on an Increasingly Frequent Surgical Problem.Geriatrics (Basel, Switzerland) · 2021Review
- Laparoscopy in Emergency: Why Not? Advantages of Laparoscopy in Major Emergency: A Review.Life (Basel, Switzerland) · 2021Review
- Cost-effectiveness analysis of nonoperative management versus open and laparoscopic surgery for uncomplicated acute appendicitis in Colombia.Cost effectiveness and resource allocation : C/E · 2021Article
- Laparoscopic Appendectomy for Acute Appendicitis Complicated by Pancytopenia in Two Patients with Hematologic Diseases.Journal of the anus, rectum and colon · 2021Article
- Managing acute appendicitis during the COVID-19 pandemic in Jiaxing, China.World journal of clinical cases · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppendicitis in elderly patients is associated with increased risk of postoperative complications. The choice between laparoscopy and open appendectomy remains controversial in treating elderly patients with appendicitis.
methodsComprehensive search of literature of MEDLINE, Embase, Cochrane Library and ClinicalTrials was done in January 2019. Studies compared laparoscopy and open appendectomy for elderly patients with appendicitis were screened and selected. Postoperative mortality, complications, wound infection, intra-abdominal abscess and operating time, length of hospital stay were extracted and analyzed. The Review Manage 5.3 was used for data analysis.
resultsTwelve studies with 126,237 patients in laparoscopy group and 213,201 patients in open group. Postoperative mortality was significantly lower following laparoscopy (OR, 0.33; 95% CI, 0.28 to 0.39). Postoperative complication and wound infection were reduced following laparoscopy ((OR, 0.65 95% CI, 0.62 to 0.67; OR,0.27, 95% CI, 0.22 to 0.32). Intra-abdominal abscess was similar between LA and OA (OR,0.44;95% CI, 0.19 to 1.03). Duration of surgery was longer following laparoscopy and length of hospital stay was shorter following laparoscopy (MD, 7.25, 95% CI, 3.13 to 11.36; MD,-2.72, 95% CI,-3.31 to - 2.13).
conclusionsNot only laparoscopy is safe and feasible, but also it is related with decreased rates of mortality, post-operative morbidity and shorter hospitalization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.