Evidence map›Paper›PMID 31137925›Full record

ArticleInternational journal of molecular sciences2019

Immunoglobulin Binding Protein 1 as a Potential Urine Biomarker in Patients with Lupus Nephritis.

Eun-Ju Lee, Oh Chan Kwon, Byeongzu Ghang, Doo-Ho Lim, Do Hoon Kim, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Eun-Ju LeeDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea. krys72@hanmail.net.
Oh Chan KwonDivision of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul 06273, Korea. lunch0422@naver.com.
Byeongzu GhangDivision of Rheumatology, Department of Medicine, Jeju National University Hospital, Jeju 63241, Korea. indream81@naver.com.
Doo-Ho LimDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan 44033, Korea. dlaengh@hanmail.net.
Do Hoon KimDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea. alakzam41@naver.com.
Seokchan HongDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea. medivineluke@gmail.com.
Chang-Keun LeeDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea. cklee@amc.seoul.kr.
Bin YooDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea. byoo@amc.seoul.kr.
Yong-Gil KimDivision of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea. bestmd2000@amc.seoul.kr.ORCID 0000-0002-8029-7355
Ulsan College · KRJeju National University Hospital · KRYonsei University · KR

Funding

Asan Institution for Life Science 2019-463National Research Foundation of Korea NRF-2016R1A6A3A11930269
6 · The paper itself

Abstract

We evaluated the role of immunoglobulin binding protein 1 (IGBP1), a phosphoprotein associated with the B cell receptor (BCR) complex, as a urine biomarker in lupus nephritis (LN). The IGBP1 concentrations in plasma and urine of patients with LN, systemic lupus erythematosus (SLE) without nephritis and healthy controls were estimated by ELISA. IGBP1 expression in the kidneys of LN patients and transplantation donors was detected by immunohistochemistry. Microarray-based global gene expression profile of HK-2 cells with

Indexed as

Adaptor Proteins, Signal TransducingAdultBiomarkersCase-Control StudiesCells, CulturedFemaleHumansIntracellular Signaling Peptides and ProteinsKidneyLupus NephritisMaleMiddle AgedMolecular ChaperonesAdaptor Proteins, Signal TransducingBiomarkersIGBP1 protein, humanIntracellular Signaling Peptides and ProteinsMolecular Chaperonesdisease activityimmunoglobulin binding protein 1inflammationLupus nephritisrenal tubular epithelial cellsurine biomarker

Identifiers

PMID31137925
PMCPMC6567280
OpenAlexW2947453544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.