Evidence map›Paper›PMID 31137924›Full record

ArticleJournal of clinical medicine2019

Thyroid Hormones and Spermatozoa: In VitroEffects on Sperm Mitochondria, Viability and DNA Integrity.

Rosita A Condorelli, Sandro La Vignera, Laura M Mongioì, Angela Alamo, Filippo Giacone, Rossella Cannarella, Aldo E Calogero

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rosita A CondorelliDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. rosita.condorelli@unict.it.
Sandro La VigneraDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. sandrolavignera@unict.it.
Laura M MongioìDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. lauramongioi@hotmail.it.
Angela AlamoDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. angela.alamo1986@gmail.com.
Filippo GiaconeDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. filippogiacone@yahoo.it.
Rossella CannarellaDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. roxcannarella@gmail.com.
Aldo E CalogeroDepartment of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy. acaloger@unict.it.
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study wasto assess the in vitro effects of levothyroxine (LT4) on conventional and bio-functional sperm parameters and its implications on fertility. Patients with male idiopathic infertility were enrolled and subjected to examination of the seminal fluid and capacitation according to the WHO 2010 criteria and flow cytometric sperm analysis for the evaluation of bio-functional sperm parameters. LT4 significantly increased the percentage of spermatozoa with high mitochondrial membrane potential (MMP), decreased the percentage of spermatozoa with low MMP and increased sperm motility already at a concentration of 0.9 pmol L

Indexed as

spermatozoasperm mitochondrial potentialsperm motilitysperm parametersthyroid hormones

Identifiers

PMID31137924
PMCPMC6571713
OpenAlexW2945155510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.