Evidence map›Paper›PMID 31137909›Full record

ArticleBrain sciences2019

Feasibility of Non-Gaussian Diffusion Metrics in Chronic Disorders of Consciousness.

Elena I Kremneva, Liudmila A Legostaeva, Sofya N Morozova, Dmitry V Sergeev, Dmitry O Sinitsyn, Elizaveta G Iazeva, Aleksandr S Suslin, Natalia A Suponeva, Marina V Krotenkova, Michael A Piradov and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Elena I KremnevaResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. kremneva@neurology.ru.
Liudmila A LegostaevaResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. milalegostaeva@gmail.com.
Sofya N MorozovaResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. kulikovasn@gmail.com.
Dmitry V SergeevResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. dmsergeev@yandex.ru.
Dmitry O SinitsynResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. d_sinitsyn@mail.ru.
Elizaveta G IazevaResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. lizaveta.mochalova@gmail.com.
Aleksandr S SuslinResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. razor1911@mail.ru.
Natalia A SuponevaResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. nasu2709@mail.ru.
Marina V KrotenkovaResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. krotenkova_mrt@mail.ru.
Michael A PiradovResearch Center of Neurology, 80 Volokolamskoe shosse, 125367 Moscow, Russia. mpi711@gmail.com.
Ivan I MaximovDepartment of Psychology, University of Oslo, Forskningsveien 3A, 0373 Oslo, Norway. ivan.maximov@psykologi.uio.no.
Research Center of Neurology · RUUniversity of Oslo · NO

Funding

Russian Science Foundation 16-15-00274
6 · The paper itself

Abstract

Diagnostic accuracy of different chronic disorders of consciousness (DOC) can be affected by the false negative errors in up to 40% cases. In the present study, we aimed to investigate the feasibility of a non-Gaussian diffusion approach in chronic DOC and to estimate a sensitivity of diffusion kurtosis imaging (DKI) metrics for the differentiation of vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS) from a healthy brain state. We acquired diffusion MRI data from 18 patients in chronic DOC (11 VS/UWS, 7 MCS) and 14 healthy controls. A quantitative comparison of the diffusion metrics for grey (GM) and white (WM) matter between the controls and patient group showed a significant (

Indexed as

chronic disorders of consciousnessdiffusion MRIDKIminimally conscious stateunresponsive wakefulness syndromevegetative state

Identifiers

PMID31137909
PMCPMC6562474
OpenAlexW2947559296

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.