ArticleMolecules (Basel, Switzerland)2019
Hypermongone C Accelerates Wound Healing through the Modulation of Inflammatory Factors and Promotion of Fibroblast Migration.
Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Antioxidant Potential ofMolecules (Basel, Switzerland) · 2026Article
- Causal Association Between Genetically Predicted Circulating Metabolites and Pressure Ulcers: A Two-Sample Mendelian Randomization Study.Journal of inflammation research · 2025Article
- Exploring the Antioxidant Potential ofNutrients · 2023Article
- Local Drug Delivery Strategies towards Wound Healing.Pharmaceutics · 2023Review
- Hypericum Genus as a Natural Source for Biologically Active Compounds.Plants (Basel, Switzerland) · 2022Review
- Phloroglucinol Derivative Carbomer Hydrogel Accelerates MRSA-Infected Wounds' Healing.International journal of molecular sciences · 2022Article
- Wound Healing Effects ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats.PloS one · 2021Article
- Therapeutic candidates for keloid scars identified by qualitative review of scratch assay research for wound healing.PloS one · 2021Review
- Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs ofMolecules (Basel, Switzerland) · 2020Article
- Effects of Hypericum scabrum extract on dentate gyrus synaptic plasticity in high fat diet-fed rats.The journal of physiological sciences : JPS · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The physiology of wound healing is dependent on the crosstalk between inflammatory mediators and cellular components of skin regeneration including fibroblasts and endothelial cells. Therefore, strategies to promote healing must regulate this crosstalk to achieve maximum efficacy. In light of the remarkable potential of natural compounds to target multiple signaling mechanisms, this study aims to demonstrate the potential of hypermongone C, a polycyclic polyprenylated acylphloroglucinol (PPAP), to accelerate wound closure by concurrently enhancing fibroblast proliferation and migration, promoting angiogenesis, and suppressing pro-inflammatory cytokines. This compound belongs to a family of plants (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.