Evidence map›Paper›PMID 31137832›Full record

ArticleMolecules (Basel, Switzerland)2019

Discovery of (3-Benzyl-5-hydroxyphenyl)carbamates as New Antitubercular Agents with Potent In Vitro and In Vivo Efficacy.

Ya-Juan Cheng, Zhi-Yong Liu, Hua-Ju Liang, Cui-Ting Fang, Niu-Niu Zhang, Tian-Yu Zhang, Ming Yan

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Juan ChengSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. chengyj397563@163.com.
Zhi-Yong LiuState Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, Guangzhou 510530, China. liu_zhiyong@gibh.ac.cn.
Hua-Ju LiangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. lianghj7@yeah.net.
Cui-Ting FangState Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, Guangzhou 510530, China. fang_cuiting@gibh.ac.cn.
Niu-Niu ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangniuniuu@yeah.net.ORCID 0000-0002-1763-4398
Tian-Yu ZhangState Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, Guangzhou 510530, China. zhang_tianyu@gibh.ac.cn.ORCID 0000-0001-5647-6014
Ming YanSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. yanming@mail.sysu.edu.cn.ORCID 0000-0001-9888-0744

Funding

Chinese Academy of Science YJKYYQ20170036Guangzhou Science Technology and Innovation Commission 201707010210, 201604020019National Natural Science Foundation of China 21772240
6 · The paper itself

Abstract

A series of 3-amino-5-benzylphenol derivatives were designed and synthesized. Among them, (3-benzyl-5-hydroxyphenyl)carbamates were found to exert good inhibitory activity against

Indexed as

Drug DiscoveryA549 CellsAnimalsAntitubercular AgentsCarbamatesCell DeathDisease Models, AnimalDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsMycobacterium tuberculosisTreatment OutcomeTuberculosisAntitubercular AgentsCarbamates(3-benzyl-5-hydroxyphenyl)carbamateantitubercular activityMycobacterium tuberculosis

Identifiers

PMID31137832
PMCPMC6572244

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.