Evidence map›Paper›PMID 31137614›Full record

ArticleInternational journal of molecular sciences2019

Impact of Pharmacological Inhibition of Hydrogen Sulphide Production in the SOD1G93A-ALS Mouse Model.

Alida Spalloni, Viviana Greco, Giulia Ciriminna, Victor Corasolla Carregari, Federica Marini, Luisa Pieroni, Nicola B Mercuri, Andrea Urbani, Patrizia Longone

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Beneficial Effects of Putative Hydrogen Sulfide (HMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Hydrogen Sulfide Signaling in Neurodegenerative Movement Disorders.Handbook of experimental pharmacology · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Advances of HAntioxidants (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alida SpalloniDepartment of Experimental Neuroscience, Molecular Neurobiology Unit, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. a.spalloni@hsantalucia.it.
Viviana GrecoFondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. viviana.greco@unicatt.it.
Giulia CiriminnaDepartment of Experimental Neuroscience, Molecular Neurobiology Unit, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. giuliaciriminna@gmail.com.ORCID 0000-0003-4896-803X
Victor Corasolla CarregariFondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. corasolla@gmail.com.
Federica MariniFondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. federica.marini@unicatt.it.
Luisa PieroniDepartment of Experimental Neuroscience, Proteomics and Metabonomics Unit, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. l.pieroni@hsantalucia.it.ORCID 0000-0001-7141-1817
Nicola B MercuriDepartment of Systems Medicine, Policlinico Universitario "Tor Vergata", University of Rome "Tor Vergata", 00133 Rome, Italy. mercurin@med.uniroma2.it.
Andrea UrbaniFondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy. andrea.urbani@unicatt.it.
Patrizia LongoneDepartment of Experimental Neuroscience, Molecular Neurobiology Unit, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. p.longone@hsantalucia.it.
Fondazione Santa Lucia · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Rome Tor Vergata · IT

Funding

Italian Department of Education and Research PRIN 20158EB2CMItalian Ministry of Health Ricerca Corrente (2017-2018)
6 · The paper itself

Abstract

A number of factors can trigger amyotrophic lateral sclerosis (ALS), although its precise pathogenesis is still uncertain. In a previous study done by us, poisonous liquoral levels of hydrogen sulphide (H

Indexed as

Aminooxyacetic AcidAmyotrophic Lateral SclerosisAnimalsBrainCells, CulturedCystathionine beta-SynthaseEnzyme InhibitorsFemaleHydrogen SulfideMaleMiceMice, Inbred C57BLNeurogliaSex FactorsSuperoxide Dismutase-1Aminooxyacetic AcidCystathionine beta-SynthaseEnzyme InhibitorsHydrogen SulfideSod1 protein, mouseSuperoxide Dismutase-1amino-oxyacetic acid (AOA)amyotrophic lateral sclerosisglial cellshydrogen sulphideinflammationpharmacology

Identifiers

PMID31137614
PMCPMC6567312
OpenAlexW2945855028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.