ArticleRadiation oncology journal2019
Interfraction variation and dosimetric changes during image-guided radiation therapy in prostate cancer patients.
Article in Radiation oncology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- An efficient automated approach for accumulated dose estimation in prostate cancer radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Patients with a Short Distance Between the Prostate and the Rectum Are Appropriate Candidates for Hydrogel Spacer Placement to Prevent Short-Term Rectal Hemorrhage After External-Beam Radiotherapy for Prostate Cancer.Current oncology (Toronto, Ont.) · 2025Article
- Ultrahypofractionated radiotherapy for localised prostate cancer: The impact of daily MRI-guided adaptive radiotherapy on delivered dose.Clinical and translational radiation oncology · 2025Article
- Using deep learning generated CBCT contours for online dose assessment of prostate SABR treatments.Journal of applied clinical medical physics · 2025Article
- Can the Dose Constraints Be Trusted? Actual Dose Exposure of Bladder and Rectum During Prostate Cancer Radiotherapy.Cancers · 2025Article
- Rectal Gas-Induced Dose Changes in Carbon Ion Radiation Therapy for Prostate Cancer: An In Silico Study.International journal of particle therapy · 2025Article
- Dosimetric impact of variable air cavity within PTV for rectum cancer.Journal of applied clinical medical physics · 2025Article
- Rectal deformation management with IGRT in prostate radiotherapy: Can it be managed with rigid alignment alone?Journal of applied clinical medical physics · 2024Article
- Prostate cancer image guided radiotherapy: Why the commotion over rectal volume and motion?Clinical and translational radiation oncology · 2023Article
- Optimizing 3DCT image registration for interfractional changes in carbon-ion prostate radiotherapy.Scientific reports · 2023Article
- The Usefulness of Adaptative Radiotherapy in Prostate Cancer: How, When, and Who?Biomedicines · 2022Article
- Bladder surface dose modeling in prostate cancer radiotherapy: An analysis of motion-induced variations and the cumulative dose across the treatment.Medical physics · 2021Article
- Quantifying the impact of SpaceOAR hydrogel on inter-fractional rectal and bladder dose during 0.35 T MR-guided prostate adaptive radiotherapy.Journal of applied clinical medical physics · 2021Article
- Low-dose CBCT reconstruction via joint non-local total variation denoising and cubic B-spline interpolation.Scientific reports · 2021Article
- Mutual Information-Based Non-Local Total Variation Denoiser for Low-Dose Cone-Beam Computed Tomography.Frontiers in oncology · 2021Article
- Feasibility of hybrid TomoHelical- and TomoDirect-based volumetric gradient matching technique for total body irradiation.Radiation oncology (London, England) · 2019Article
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6 authors.
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Abstract
purposeThe aim of this study was to identify volume changes and dose variations of rectum and bladder during radiation therapy in prostate cancer (PC) patients. MATERIALS AND
methodsWe analyzed 20 patients with PC treated with helical tomotherapy. Daily image guidance was performed. We re-contoured the entire bladder and rectum including its contents as well as the organ walls on megavoltage computed tomography once a week. Dose variations were analyzed by means of Dmedian, Dmean, Dmax, V10 to V75, as well as the organs at risk (OAR) volume. Further, we investigated the correlation between volume changes and changes in Dmean of OAR.
resultsDuring treatment, the rectal volume ranged from 62% to 223% of its initial volume, the bladder volume from 22% to 375%. The average Dmean ranged from 87% to 118% for the rectum and 58% to 160% for the bladder. The Pearson correlation coefficients between volume changes and corresponding changes in Dmean were -0.82 for the bladder and 0.52 for the rectum. The comparison of the dose wall histogram (DWH) and the dose volume histogram (DVH) showed that the DVH underestimates the percentage of the rectal and bladder volume exposed to the high dose region.
conclusionRelevant variations in the volume of OAR and corresponding dose variations can be observed. For the bladder, an increase in the volume generally leads to lower doses; for the rectum, the correlation is weaker. Having demonstrated remarkable differences in the dose distribution of the DWH and the DVH, the use of DWHs should be considered.
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