Evidence map›Paper›PMID 31136714›Full record

ArticleACS infectious diseases2019

Antibiofilm Efficacy of Nitric Oxide-Releasing Alginates against Cystic Fibrosis Bacterial Pathogens.

Mona Jasmine R Ahonen, Jamie M Dorrier, Mark H Schoenfisch

Abstract read
In one paragraph

Article in ACS infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Biopolymeric Inhalable Dry Powders for Pulmonary Drug Delivery.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  3. Review
  4. How Three Self-Secreted Biofilm Exopolysaccharides ofInternational journal of molecular sciences · 2023
    Review
  5. Biofilm Formation byInternational journal of molecular sciences · 2022
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Role of Nitric Oxide-Releasing Glycosaminoglycans in Wound Healing.ACS biomaterials science & engineering · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mona Jasmine R AhonenDepartment of Chemistry , University of North Carolina at Chapel Hill , CB 3290, Chapel Hill , North Carolina 27599 , United States.
Jamie M DorrierDepartment of Chemistry , University of North Carolina at Chapel Hill , CB 3290, Chapel Hill , North Carolina 27599 , United States.
Mark H SchoenfischDepartment of Chemistry , University of North Carolina at Chapel Hill , CB 3290, Chapel Hill , North Carolina 27599 , United States.ORCID 0000-0002-2212-0658

Funding

Nitric oxide-releasing cystic fibrosis therapeuticsR21AI112029 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SCHOENFISCH, MARK H · 2015 to 2016
$404k
NIAID NIH HHS R21 AI112029
6 · The paper itself

Abstract

Colonization of the lungs by biofilm-forming pathogens is a major cause of mortality in cystic fibrosis (CF). In CF patients, these pathogens are difficult to treat due to the additional protection provided by both the biofilm exopolysaccharide matrix and thick, viscous mucus. The antibiofilm efficacy of nitric oxide (NO)-releasing alginates was evaluated against

Indexed as

AerobiosisAlginatesAnaerobiosisAnti-Bacterial AgentsBacteriaBiofilmsCystic FibrosisKineticsMicrobial Sensitivity TestsNitric OxideOligosaccharidesAlginatesAnti-Bacterial AgentsNitric OxideOligosaccharidesalginatesantibiofilmcystic fibrosisnitric oxide

Identifiers

PMID31136714
PMCPMC6773255

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.