ArticlePloS one2019
Genetic and environmental factors influencing the contents of essential oil compounds in Atractylodes lancea.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Atractylodis Rhizoma: A review of its traditional uses, phytochemistry, pharmacology, toxicology and quality control.Journal of ethnopharmacology · 2021Pooled it
- Chromosome-scale genome assembly and genomic prediction of essential oil compounds in Atractylodes lancea for genomics-assisted breeding.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026Article
- Antifungal Potential of Essential Oils From Native Mexican Species: Chemical Composition and In Vitro Vapor-Phase Analyses.Chemistry & biodiversity · 2026Article
- A Systematic Review on Functional Bioactive Compound Atractylone: Natural Source, Pharmacological Properties and Mechanisms Insights.Food science & nutrition · 2026Review
- Multivariate edaphic gradients are associated with phytochemical quality variation inFrontiers in plant science · 2026Article
- Chemical Composition and Biological Activities of Bubonium graveolens (Forssk) Maire Essential Oil: In Silico Evaluation of Its Major Compounds.Chemistry & biodiversity · 2026Article
- The combined influence of microbiome and soil environment contributes to the chemotype differentiation iniMetaOmics · 2025Article
- Genome-wide identification and expression analysis of the WRKY transcription factors related to sesquiterpenes biosynthesis inFrontiers in genetics · 2025Article
- Article
- Induction and metabolomic analysis of hairy roots of Atractylodes lancea.Applied microbiology and biotechnology · 2023Article
- Geographic Differentiation of Essential Oil from Rhizome of CultivatedMolecules (Basel, Switzerland) · 2023Article
- Authenticating the geographic origins ofFrontiers in plant science · 2023Article
- Volatile Oils Discrepancy between Male and FemalePlants (Basel, Switzerland) · 2022Article
- Chemical Diversity of Essential Oils from Korean Native Populations ofMolecules (Basel, Switzerland) · 2022Article
- Distribution Patterns of Essential Oil Terpenes in Native and InvasivePlants (Basel, Switzerland) · 2022Article
- Drought stress modifies the community structure of root-associated microbes that improveFrontiers in plant science · 2022Article
- Comparison of the Effects of Essential Oil Obtained from the Crude and Bran-ProcessedEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Evaluation of heritability of β-eudesmol/hinesol content ratio in Atractylodes lancea De Candolle.Hereditas · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhizomes of Atractylodes lancea are used in traditional Japanese medicine (Kampo) and Chinese medicine to treat numerous diseases and disorders because they contain many pharmacologically active compounds. The major active compounds in A. lancea are essential oil compounds such as β-eudesmol, hinesol, atractylon, and atractylodin. The contents of the compounds in A. lancea exhibit high variability depending on their habitat. We cultivated clonal lines of A. lancea in different years (2016, 2017) and different locations (Hokkaido, Ibaraki) to investigate the influence of genetic and environmental factors on the contents of major compounds, namely, β-eudesmol, hinesol, atractylon, and atractylodin. Broad sense heritability of β-eudesmol, hinesol, atractylon, and atractylodin contents were 0.84, 0.77, 0.86, and 0.87, respectively. The effects of interannual variability on the contents of the compounds were lower than those of genotype. In addition, the cultivated environmental factors were assessed by different locations, and the correlations between Hokkaido and Ibaraki grown plants based on β-eudesmol, hinesol, atractylon, and atractylodin contents were 0.94, 0.94, 1.00, and 0.83, respectively. The results suggest that the contents of β-eudesmol, hinesol, atractylon, and atractylodin in A. lancea are largely influenced by genetic factors, and clonal propagation could be an effective strategy for obtaining populations with high contents of essential oil compounds. Furthermore, the contents of β-eudesmol, hinesol, atractylon, and atractylodin in A. lancea exhibited few correlations with rhizome yields. A. lancea cultivars with not only high contents of essential oil compounds but also high rhizome yield could be developed through selective breeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.