Evidence map›Paper›PMID 31136536›Full record

ArticleNuclear medicine communications2019

Positional dependence of activity determination in single photon emission computed tomography.

Emlyn Price, Jill Tipping, David M Cullen, Nick Calvert, David Hamilton, Emma Page, Sophia Pells, Ben Pietras, Andrew P Robinson

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nuclear medicine communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Emlyn PriceSchuster Laboratory, School of Physics and Astronomy, The University of Manchester.
Jill TippingChristie Medical Physics and Engineering (CMPE), The Christie NHS Foundation Trust, Manchester.
David M CullenSchuster Laboratory, School of Physics and Astronomy, The University of Manchester.
Nick CalvertChristie Medical Physics and Engineering (CMPE), The Christie NHS Foundation Trust, Manchester.
David HamiltonChristie Medical Physics and Engineering (CMPE), The Christie NHS Foundation Trust, Manchester.
Emma PageSchuster Laboratory, School of Physics and Astronomy, The University of Manchester.
Sophia PellsSchuster Laboratory, School of Physics and Astronomy, The University of Manchester.
Ben PietrasSchuster Laboratory, School of Physics and Astronomy, The University of Manchester.
Andrew P RobinsonNational Physical Laboratory, Teddington, UK.
The Christie NHS Foundation Trust · GBUniversity of Manchester · GBNational Physical Laboratory · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate image quantification requires accurate calibration of the detector and is vital if dosimetry is to be performed in molecular radiotherapy. A dependence on the position of calibration has been observed in single photon emission computed tomography images when attenuation correction (AC) and scatter correction are applied. This work investigates the origin of this dependence in single photon emission computed tomography scans of phantom inserts filled with Lu solution. A 113 ml sphere and inserts representing a mathematical model of a spleen and an anatomical model of a patient spleen were imaged at the centre and edge of elliptical phantoms. For these inserts, the difference in calibration factor between the positions was around 10% for images reconstructed with AC and triple energy window scatter correction. A combination of experimental imaging and Monte Carlo simulation was used to isolate possible causes due to imaging or reconstruction in turn. Inconsistent application of AC between different reconstruction systems was identified as the origin of the positional dependence.

Indexed as

Image Processing, Computer-AssistedTomography, Emission-Computed, Single-PhotonCalibrationScattering, Radiation

Identifiers

PMID31136536
PMCPMC6635063
OpenAlexW2946797278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.