ArticleClinical and translational gastroenterology2019
Impact of Preoperative Nutritional Status on the Incidence Rate of Surgical Complications in Patients With Inflammatory Bowel Disease With Vs Without Preoperative Biologic Therapy: A Case-Control Study.
Article in Clinical and translational gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07125859 (Prevalence of Preoperative Malnutrition and Changes in Nutritional Status Following Preoperative Nutrition Education in Surgical Patients Attending a Preoperative Clinic), which is not on this map. Cited by 16 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevalence of Preoperative Malnutrition and Changes in Nutritional Status Following Preoperative Nutrition Education in Surgical Patients Attending a Preoperative Clinic
Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease.Nutrients · 2023Pooled it
- Perioperative Management of Ulcerative Colitis: A Systematic Review.Diseases of the colon and rectum · 2022Pooled it
- Abdominal hernia mesh repair in patients with inflammatory bowel disease: A systematic review.Langenbeck's archives of surgery · 2022Pooled it
- Association between vedolizumab and postoperative complications in IBD: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024Article
- A foundational approach to culture and analyze malnourished organoids.Gut microbes · 2023Article
- Risk and management of post-operative infectious complications in inflammatory bowel disease: A systematic review.World journal of gastrointestinal surgery · 2023Article
- Nascent to novel methods to evaluate malnutrition and frailty in the surgical patient.JPEN. Journal of parenteral and enteral nutrition · 2023Review
- Perioperative optimization of Crohn's disease.Annals of gastroenterological surgery · 2023Review
- Handgrip strength and risk of malnutrition are associated with an increased risk of hospitalizations in inflammatory bowel disease patients.Therapeutic advances in gastroenterology · 2023Article
- Timing of individualized surgical intervention in Crohn's disease.World journal of gastrointestinal surgery · 2022Review
- Risk of Infections with Anti-TNF Agents in Patients with Crohn's Disease After Elective Surgery.Digestive diseases and sciences · 2022Article
- Coronary Microvascular Dysfunction Restored After Surgery in Inflammatory Bowel Disease: A Prospective Observational Study.Journal of the American Heart Association · 2021Observational
- Exploring the Relationship between Biologics and Postoperative Surgical Morbidity in Ulcerative Colitis: A Review.Journal of clinical medicine · 2021Review
- [Drug treatment of chronic inflammatory bowel diseases-What must the surgeon know and perioperatively pay attention to?]Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Biologics and surgical outcomes in Crohn's disease: is there a direct relationship?Therapeutic advances in gastroenterology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesA case-control study was undertaken to assess the impact of preoperative nutrition on surgical outcomes in patients with inflammatory bowel disease with vs without preoperative biologic therapy.
methodsSeventy patients who had received biologic therapy within 8 weeks before undergoing resection for active ulcerative colitis (n = 34) or Crohn's disease (n = 36) were included (BIO group). The control group comprised 70 patients without exposure to biologics, selected based on 5 matching criteria: inflammatory bowel disease subtype (ulcerative colitis/Crohn's disease), age (≤ or >40 years), disease severity (moderate/severe), surgical approach (open/laparoscopic), and main surgical procedure. Poor nutrition was defined as the presence of at least one of the following criteria: weight loss >10%-15% within 6 months, body mass index <18.5 kg/m, Subjective Global Assessment Grade C, or serum albumin <30 g/L.
resultsThe proportion of patients with preoperative poor nutrition was 43% in the BIO and 33% in the control groups (P = 0.22). The incidence of postoperative infectious complications (anastomotic leak, intra-abdominal abscess, enterocutaneous fistula, or wound infection) was 16% in the BIO and 14% in the control groups (P = 0.81). In the BIO group, poor nutrition significantly increased the risk of infectious complications (27% vs 8% without poor nutrition, P = 0.03). In addition, in the control group, the incidence of infectious complications was higher in patients with poor nutrition, but not significantly (22% vs 11%, P = 0.21). DISCUSSION: Poor nutrition increases the risk of infectious complications after surgery. The detrimental effects of poor nutrition on postsurgical infection may be enhanced in patients who have received biologic therapy preoperatively.
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