Evidence map›Paper›PMID 31136202›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2019

Heat therapy improves glucose tolerance and adipose tissue insulin signaling in polycystic ovary syndrome.

Brett R Ely, Zachary S Clayton, Carrie E McCurdy, Joshua Pfeiffer, Karen Wiedenfeld Needham, Lindan N Comrada, Christopher T Minson

Registry-linked trialOpen access · bronzeAbstract readControlled Clinical Trial
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07158047 (Targeting Hypertension and Insulin Resistance With Heat Therapy), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07158047 narecruitingnot on this mapstarted 2022, after this paper: background citation

Targeting Hypertension and Insulin Resistance With Heat Therapy

TypeinterventionalSponsorUniversity of OregonRan2022 to 2026Enrolled20ConditionsObesity (Disorder)ArmsHeat therapy
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Adipose Tissue Dysfunction in Polycystic Ovary Syndrome.The Journal of clinical endocrinology and metabolism · 2023
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Diabetes, Protein Misfolding, and Heat Stress: Molecular Insights and Translational Perspectives.TH open : companion journal to thrombosis and haemostasis · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Comparison of thermoregulatory, cardiovascular, and immune responses to different passive heat therapy modalities.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brett R ElyDepartment of Human Physiology, University of Oregon , Eugene, Oregon.ORCID 0000-0002-8062-4475
Zachary S ClaytonDepartment of Human Physiology, University of Oregon , Eugene, Oregon.
Carrie E McCurdyDepartment of Human Physiology, University of Oregon , Eugene, Oregon.ORCID 0000-0003-1177-9040
Joshua PfeifferPeaceHealth Medical Group, Oregon Bariatric Center , Springfield, Oregon.
Karen Wiedenfeld NeedhamDepartment of Human Physiology, University of Oregon , Eugene, Oregon.
Lindan N ComradaDepartment of Human Physiology, University of Oregon , Eugene, Oregon.
Christopher T MinsonDepartment of Human Physiology, University of Oregon , Eugene, Oregon.
University of Oregon · USPeaceHealth St. John Medical Center · US

Funding

TRAINING IN RENAL &ELECTROLYTE DISEASE &HYPERTENSIONT32DK007135 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JOHNSON, RICHARD JOSEPH, KENDRICK, JESSICA B · 1986 to 2024
$5.3M
NIDDK NIH HHS T32 DK007135
6 · The paper itself

Abstract

Polycystic ovary syndrome (PCOS) is associated with high rates of obesity and metabolic dysfunction. Repeated passive heat exposure (termed heat therapy) is a novel lifestyle intervention for improving health in obese women with PCOS. The purpose of this study was to examine changes in metabolic function in obese women with PCOS following heat therapy. Eighteen age- and BMI-matched obese women with PCOS (age: 27 ± 1 yr, BMI: 41.3 ± 1.1 kg/m

Indexed as

Adipose TissueAdultBlood GlucoseBody Mass IndexFemaleGlucose Tolerance TestHot TemperatureHumansImmersionInsulinInsulin ResistanceMiddle AgedObesityPolycystic Ovary SyndromeBlood GlucoseInsulinadipose tissue inflammationheat shock proteininsulin resistancepassive heating

Identifiers

PMID31136202
PMCPMC7199222
OpenAlexW2947521233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.